Results 301 to 310 of about 2,050,605 (416)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Pervenous Pacing of the Specialized Conducting System in Man [PDF]

open access: bronze, 1970
Onkar S. Narula   +2 more
openalex   +1 more source

Correction: <i>TP53</i> drives invasion through expression of its Δ133p53β variant.

open access: yesElife
Gadea G   +19 more
europepmc   +1 more source

The essentials of cardiac pacing [PDF]

open access: green, 1978
G Fontaine   +3 more
openalex   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya   +3 more
wiley   +1 more source

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