Results 311 to 320 of about 2,050,605 (416)

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

FEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei, Amir Barzegar Behrooz, Marco Cordani, Mahmoud Aghaei, Negar Azarpira, Daniel J. Klionsky, Saeid Ghavami   +6 more
wiley   +1 more source

Cardiac standstill due to digoxin poisoning successfully treated with atrial pacing. [PDF]

, 1973
Dennis L. Citrin, K O'Malley, W S Hillis
openalex   +1 more source

Efficacy of VDT PACE‐like regimens in treatment of relapsed/refractory multiple myeloma

American journal of hematology/oncology, 2018
A. Lakshman, Preet Paul Singh, S. Rajkumar, A. Dispenzieri, M. Lacy, M. Gertz, F. Buadi, D. Dingli, Y. Hwa, A. Fonder, M. Hobbs, S. Hayman, S. Zeldenrust, J. Lust, S. Russell, N. Leung, P. Kapoor, R. Go, Yi Lin, W. Gonsalves, T. Kourelis, R. Warsame, R. Kyle, Shaji K. Kumar   +23 more
semanticscholar   +1 more source

Current interpretations of the I-PACE model of behavioral addictions. [PDF]

J Behav Addict
Brand M, Müller A, Wegmann E, Antons S, Brandtner A, Müller SM, Stark R, Steins-Loeber S, Potenza MN.   +8 more
europepmc   +1 more source

An enzyme‐linked immunosorbent assay (ELISA)‐based activity assay for AMP‐activated protein kinase (AMPK)

FEBS Open Bio, EarlyView.
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley   +1 more source

Environmental Variability Shapes Life History of the World's Birds. [PDF]

Ecol Lett
Youngflesh C, Kapsar K, Uscanga A, Williams PJ, Doser JW, Kounta L, Zarnetske PL.   +6 more
europepmc   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Bantu expansion shows that habitat alters the route and pace of human dispersals

Proceedings of the National Academy of Sciences of the United States of America, 2015
R. Grollemund, S. Branford, K. Bostoen, A. Meade, C. Venditti, M. Pagel   +5 more
semanticscholar   +1 more source

European general practitioners' attitudes towards person-centred care and factors that influence its implementation in everyday practice: The protocol of the cross-sectional PACE GP/FP study in 24 European countries. [PDF]

Eur J Gen Pract
Petriček G, Klemenc-Ketiš Z, Ožvačić Adžić Z, Cerovečki V, Willems S, Tsimtsiou Z, Zelko E, Collins C, Hoffmann K, Eide TB, Ares Blanco S, Frese T, Lingner H, Assenova R, Torzsa P, Seifert B, Ungan M, Bayen S, Windak A, Azeredo J, Stavrikj K, Kreitmayer S, Kostić M, Busneag IC, Koskela T, Serafini A, Butterworth J, Zwart DLM, González-Lama J, Vuletić G, Van Poel E, Tušek Bunc K, Tuz C, Mevsim V, Seifert M, Dahli M, Hrabač P, Hanževački M, Rakić Matić J, Tomičić M, Rađa M, Heleno B, Studzinski K, Becze Á, Megallón-Botaya R, Rogers HL, Brütting C, Kafadar D, Lerma Irureta D, Fornacciari D, Nessler K, Soleski K, Méndez-López F, Çöme O, Ahmad A, Petek D.   +55 more
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source