Results 121 to 130 of about 290,996 (382)

The Circadian Transcription Factor CLOCK Modulates Oxidative Stress Resistance via the ACHL–Relish Axis in Drosophila

open access: yesAdvanced Science, EarlyView.
This study identifies the circadian transcription factor CLOCK (CLK) as a key regulator of oxidative stress resistance in fruit flies. CLK controls immune responses by driving rhythmic transcription of an RNA‐binding protein‐Achilles (ACHL) in the fly brain, which post‐transcriptionally represses the NF‐κB homolog Relish, limiting immune activation and
Xu Liu   +7 more
wiley   +1 more source

پیش‌بینی قابلیت القای تاکی‌کاردی بطنی بر اساس قابلیت هدایت بطن به دهلیز در بیماران مشکوک به تاکی‌آریتمی بطنی

open access: yesمجله دانشکده پزشکی اصفهان, 2010
مقدمه: امکان پیش‌بینی قابلیت القای تاکی‌کاردی بطنی از طریق فاکتورهای بالینی و نیز قابلیت هدایت بطن به دهلیز، شناسایی بیماران پر خطر برای تاکی‌آریتمی بطنی را آسان‌تر می‌کند. روش‌ها: تعداد 54 نفر از مراجعین به درمانگاه‌های بیمارستان چمران اصفهان، که به علت
Mohammad Reza Samiei nasab   +2 more
doaj  

Barnes Hospital Bulletin [PDF]

open access: yes, 1976
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1121/thumbnail ...

core   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

Dissolution Study of Biodegradable Magnesium Silicide Thin Films for Transient Electronic Applications

open access: yesAdvanced Science, EarlyView.
Magnesium silicide (Mg2Si) is introduced as a narrow‐bandgap, biodegradable semiconductor for transient electronics. RF‐sputtered and annealed Mg2Si thin films show high intrinsic electrical conductivity and low thermal conductivity. The polycrystalline material undergoes hydrolysis in aquatic and composting environments with minimal cytotoxicity ...
Ji‐Woo Gu   +17 more
wiley   +1 more source

Genetically engineered cardiac pacemaker: stem cells transfected with HCN2 gene and myocytes - a model

open access: yes, 2005
Artificial biological pacemakers were developed and tested in canine ventricles. Next steps will require obtaining oscillations sensitive to external regulations, and robust with respect to long term drifts of expression levels of pacemaker currents and ...
Kanani, Sandra   +2 more
core  

Deterioration of autonomic neuronal receptor signaling and mechanisms intrinsic to heart pacemaker cells contribute to age‐associated alterations in heart rate variability in vivo

open access: yesAging Cell, 2016
We aimed to determine how age‐associated changes in mechanisms extrinsic and intrinsic to pacemaker cells relate to basal beating interval variability (BIV) reduction in vivo.
Y. Yaniv   +9 more
semanticscholar   +1 more source

Efficacy of Sequential Hepatic Vein Embolization Following Portal Vein Embolization in Promoting Regeneration of Liver Volume and Function Before Right‐Sided Major Hepatectomy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Sequential hepatic vein embolization (HVE) following portal vein embolization (PVE) significantly improves both the volume and function of the future remnant liver (FRL) compared to PVE alone. In this study, the FRL regeneration rates for volume and function were markedly higher and faster in the PVE–HVE group, with no differences in surgical outcomes ...
Thanh Tung Lai   +9 more
wiley   +1 more source

Unusual Case of Colonized Pacemaker Lead Presenting with Endocarditis, Hemoptysis and Tricuspid Valve Stenosis

open access: yesCanadian Respiratory Journal, 2011
The present report is the first to describe a case of hemoptysis caused by an endocardial pacemaker lead. In addition, the patient presented with endocarditis and tricuspid valve stenosis.
Jean-Francois Morin   +2 more
doaj   +1 more source

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