Results 141 to 150 of about 294,782 (382)

Brugada Syndrome: New Implications for Heterozygous Carriers of the Pathogenic SCN5A c.689T>C(p.Ile230Thr) Variant

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in the SCN5A gene and its subunits have been identified in individuals with Brugada Syndrome. One such SCN5A variant, c.689T>C(p.Ile230Thr), was previously reported as disease‐causing only in homozygous individuals, with heterozygous carriers being unaffected.
Shayla Shojaat   +2 more
wiley   +1 more source

The relationship between psychosocial job stressors and insomnia: The mediating role of psychological capital

open access: yesNursing Open, EarlyView., 2023
Abstract Aim This study aimed to examine the association of job‐related stressors and insomnia; to determine the association of psychological capital and insomnia; and to explore whether psychological capital mediates the association between job‐related stressors and insomnia among Chinese nurses. Design A cross‐sectional questionnaire survey.
Juan Du   +8 more
wiley   +1 more source

Arrhythmia diagnosis using a permanent pacemaker

open access: gold, 2022
Abdullah Orhan Demirtaş   +3 more
openalex   +1 more source

Resilience to Endoplasmic Reticulum Stress Mitigates Membrane Hyperexcitability Underlying Late Disease Onset in a Murine Model of SCA6

open access: yesAnnals of Neurology, EarlyView.
Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang   +10 more
wiley   +1 more source

Concealed malfunction of the temporary pacemaker

open access: yesIndian Pacing and Electrophysiology Journal, 2006
The 12-lead ECG shows sequential atrial and ventricular pacing (Figure 1A). A tracing, obtained simultaneously during pacemaker interrogation, disclosed pacemaker functioning as VDD mode (Figure 1B).
Mohammad Alasti   +3 more
doaj  

Temporary Endocavitary Pacemakers and their Use and Misuse: The Least is Better

open access: yesClinical Medicine Insights: Cardiology, 2014
Temporary pacemakers are classically indicated for severe bradydysrhythmia, especially when the clinical settings require prompt intervention. Implantation of a temporary pacemaker is not a benign procedure since it may be associated with serious adverse
Antoine Kossaify
doaj   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

open access: yesArthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman   +2 more
wiley   +1 more source

Genetically engineered cardiac pacemaker: stem cells transfected with HCN2 gene and myocytes - a model

open access: yes, 2005
Artificial biological pacemakers were developed and tested in canine ventricles. Next steps will require obtaining oscillations sensitive to external regulations, and robust with respect to long term drifts of expression levels of pacemaker currents and ...
Kanani, Sandra   +2 more
core  

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