Results 171 to 180 of about 96,497 (267)

Two Novel ACTC1 Variants Cause Arthrogryposis Multiplex Congenita

Clinical Genetics, EarlyView.
We report on two individuals with arthrogryposis multiplex congenita who were heterozygous for ACTC1 missense variants (NM_005159.5; c.325G>A, p.Glu109Lys and c.650A>C, p.Lys217Thr) and provide a characterization of these variants through in vitro studies.
Lauren Kerr, Pierre Moffatt, Lauren Hyer, Sarah Nossov, Noémi Dahan‐Oliel, Frank Rauch   +5 more
wiley   +1 more source

Temporary Rhythm Control with Flecainide in Atrial Fibrillation-Related Conversion Pauses Prior to Catheter Ablation: A Case of Successful Pharmacological Bridging. [PDF]

Int Med Case Rep J
Skakun O, Varunkiv O, Symchych A, Symchych K, Vandzhura I, Vandzhura Y, Denina R, Zvonar P, Rudnyk V.   +8 more
europepmc   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

European Journal of Haematology, EarlyView.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto, Silvia Sorella, Erminia Baldacci, Massimo Breccia, Sabina Chiaretti, Marcello Capriata, Livia Donzelli, Gianna Maria D'Elia, Salvatore Giacomo Morano, Ilaria Del Giudice, Maurizio Martelli, Cristina Santoro, Antonio Chistolini   +12 more
wiley   +1 more source

Novel technique for leadless pacemaker implantation in the small right atrial appendage: a case report. [PDF]

Eur Heart J Case Rep
Watanabe H, Mizutani Y, Watanabe J, Yanagisawa S, Murohara T.   +4 more
europepmc   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

AAV-mediated long-term TBX18 expression causes cardiac fibrosis and fails to induce pacemaker activity in rodents. [PDF]

J Clin Invest
Wang J, Rivaud MR, Klerk M, Boender AR, Visser RN, Sparrius R, Lee HY, van Duijvenboden K, Zhou H, Yang Y, Kramer EJ, Park KH, Park LC, Schrödel S, Thirion C, Ehrke-Schulz E, Ehrhardt A, Kirzner OF, Neef K, Tan HL, Verkerk AO, Christoffels VM, Boink GJ.   +22 more
europepmc   +1 more source

Bioimpedance and Symptom Guided Fluid Management in Hemodialysis: A Multicenter Pre–Post Implementation Study

Hemodialysis International, EarlyView.
ABSTRACT Background Optimizing volume status is central to hemodialysis care and may influence patient‐reported outcome measures as recovery time. We evaluated the implementation of a structured decision aid (Recova) integrating symptom assessment with bioimpedance spectroscopy in routine hemodialysis practice.
Maaike Nielen, Maria K. Svensson, Hans Furuland, Ursa Bonnevier, Ainhoa Indurain, Annica Sedin, Michael Eklund, Jenny Stenberg   +7 more
wiley   +1 more source

Heart Transplantation Requiring Permanent Pacemaker: Risk Factors and Outcomes. [PDF]

J Clin Med
Keller M, Kwon YIC, Haghighi Y, Kasirajan V, Hashmi Z.   +4 more
europepmc   +1 more source

Effectiveness of Toothbrush Containing Solar Cells and Titanium Dioxide Rod on Plaque Reduction During Caregiver‐Performed Toothbrushing—Randomised Crossover Clinical Trial

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives This study was conducted to assess the effectiveness of a toothbrush containing solar cells and a titanium dioxide electrode (TiO2 toothbrush) compared with a normal toothbrush for removing plaque during caregiver‐performed oral hygiene care for elderly residents in nursing homes who require care. Methods A randomised, double‐blind,
Jumpei Murakami, Mai Niida
wiley   +1 more source

Circadian Deregulation in Multiple Myeloma: BMAL1/CLOCK Expression Patterns and Diagnostic Performance

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Circadian clock disruption has emerged as a relevant axis in cancer; however, the expression patterns and diagnostic relevance of BMAL1 and CLOCK in multiple myeloma (MM) remain insufficiently defined. Methods BMAL1 and CLOCK mRNA expression was quantified by RT‐qPCR in bone marrow samples from 46 newly diagnosed MM patients and 13 ...
Hamide Albayrak, Mustafa Ertan Ay, Anıl Tombak, Kenan Çevik, Özlem İzci Ay, Tuba Kabasakal, Mehmet Emin Erdal   +6 more
wiley   +1 more source