Results 11 to 20 of about 110,223 (206)
Bruton tyrosine kinase inhibitors in the management of Waldenström macroglobulinemia
Abstract Bruton tyrosine kinase (BTK) inhibitors have taken a central role in the management of patients with Waldenström macroglobulinemia and are the only agents approved by the Food and Drug Administration (FDA) to treat these patients. Although associated with high rates of durable responses, unmet needs with BTK inhibitor therapy include ...
Jorge J. Castillo+4 more
wiley +1 more source
WD patients with dystonia were more susceptible to suffer from low BMI and highߚlevel neurological dysfunctions. It was the first time to apply the PSE of EEG to detect the cortical synaptic activity in WD patients. The cortical activities of the WD patients with dystonia seemed to be more chaotic during the eyes‐closed and reading tasks but lower ...
Shaoru Zhang+9 more
wiley +1 more source
Evidence of emerging BBB changes in mid‐age apolipoprotein E epsilon‐4 carriers
This study demonstrated a tendency towards BBB permeability in APOEε4 participants emerging from mid‐age, with quantitative differences observable on a number of the measures. Results from this study may help identify at‐risk populations at an early stage which will be crucial in facilitating the development of early interventions to change the ...
Nourah M. Alruwais+3 more
wiley +1 more source
Abstract Purpose Our purpose was to explore the relationship between cognitive impairment and neural network changes in patients newly diagnosed with self‐limited epilepsy with centrotemporal spikes (SeLECTS). Methods The Wechsler Intelligence Scale for Children, fourth edition was used to divide all SeLECTS patients into two groups: patients with full‐
Yihan Li+7 more
wiley +1 more source
Modeling circadian and sleep-homeostatic effects on short-term interval timing [PDF]
Short-term interval timing i.e., perception and action relating to durations in the seconds range, has been suggested to display time-of-day as well as wake dependent fluctuations due to circadian and sleep-homeostatic changes to the rate at which an ...
Aritake, Sayaka+7 more
core +2 more sources
Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity. [PDF]
The origin of sinoatrial node (SAN) pacemaker activity in the heart is controversial. The leading candidates are diastolic depolarization by "funny" current (If) through HCN4 channels (the "Membrane Clock" hypothesis), depolarization by cardiac Na-Ca ...
Alber, Sarah+13 more
core +2 more sources
Abstract Background Clinical factors favouring coronary angiography (CA) selection and variables associated with in‐hospital mortality among patients presenting with out‐of‐hospital cardiac arrest (OHCA) without ST‐segment elevation (STE) remain unclear.
Wayne C. Zheng+15 more
wiley +1 more source
Can we use verbal estimation to dissect the internal clock? Differentiating the effects of pacemaker rate, switch latencies, and judgment processes [PDF]
Behavioural timing is frequently assumed to be based on the accumulation of pulses from a pacemaker. In humans, verbal estimation is often used to determine whether the effect of factors which influence subjective time become more pronounced at longer ...
Allan+35 more
core +1 more source
Abstract Objectives This study evaluates the impact of transcatheter tricuspid valve interventions (TTVI) on cognitive function (CF), quality of life (QOL), and exercise capacity in late‐stage heart failure with preserved ejection fraction (HFpEF) and relevant tricuspid regurgitation (TR).
Muhammed Gerçek+7 more
wiley +1 more source
Extracting topological features from dynamical measures in networks of Kuramoto oscillators [PDF]
The Kuramoto model for an ensemble of coupled oscillators provides a paradigmatic example of non-equilibrium transitions between an incoherent and a synchronized state.
A. Barrat+9 more
core +2 more sources