Results 61 to 70 of about 91,084 (248)

Implementation of First‐Line Rapid Genome Sequencing for Children in Pediatric and Cardiac Intensive Care Units

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Substantial data supports the use of rapid exome and genome sequencing (rES/rGS) in Neonatal Intensive Care Units (NICU), but fewer studies have examined the impact of rES/rGS in other pediatric critical care units. We evaluated the impact on diagnostic yield and time to diagnosis following a single‐center hospital policy change allowing ...
Alexandra C. Keefe, Abbey A. Scott, Lukas Kruidenier, Jessie Conta, Darci L. Sternen, Sarah V. Clowes Candadai, Shannon M. Stasi, Julia Parish‐Morris, Megan Sikes, Margaret P. Adam, Anita E. Beck, Jennifer C. Hayek, Ian Glass, James T. Bennett, Ghayda Mirzaa, Paul Kruszka, Britt Johnson, Kirsty McWalter, Deborah Copenheaver, Bethany Friedman, Michael Bamshad, Katrina M. Dipple, Tara L. Wenger   +22 more
wiley   +1 more source

Anesthetic considerations and successful management of a patient with permanent pacemaker for cervical spine instrumentation

Saudi Journal of Anaesthesia, 2018
Patients with permanent pacemaker posted for cervical spine instrumentation pose special challenges for modern-day anesthesiologist since the field of surgery is in proximity to the pacing apparatus.
Vattipalli Sameera, Mihir P Pandia, Barkha Bindu, Keshav Goyal   +3 more
doaj   +1 more source

Brugada Syndrome: New Implications for Heterozygous Carriers of the Pathogenic SCN5A c.689T>C(p.Ile230Thr) Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in the SCN5A gene and its subunits have been identified in individuals with Brugada Syndrome. One such SCN5A variant, c.689T>C(p.Ile230Thr), was previously reported as disease‐causing only in homozygous individuals, with heterozygous carriers being unaffected.
Shayla Shojaat, Benjamin Hale, Taylor Warner   +2 more
wiley   +1 more source

Early Pacemaker Dependency After Heart Transplantation Is Associated with Permanent Pacemaker Implantation, Graft Failure and Mortality

Journal of Cardiovascular Development and Disease
Aims: Patients after heart transplantation (HTX) often experience post-transplant bradycardia, but little is known about the outcomes of early pacemaker dependency after HTX.
Fabrice F. Darche, Karsten M. Heil, Rasmus Rivinius, Matthias Helmschrott, Philipp Ehlermann, Norbert Frey, Ann-Kathrin Rahm   +6 more
doaj   +1 more source

SHOX2 Overexpression Favors Differentiation of Embryonic Stem Cells into Cardiac Pacemaker Cells, Improving Biological Pacing Ability

Stem Cell Reports, 2015
Summary: When pluripotency factors are removed, embryonic stem cells (ESCs) undergo spontaneous differentiation, which, among other lineages, also gives rise to cardiac sublineages, including chamber cardiomyocytes and pacemaker cells. Such heterogeneity
Vittoria Ionta, Wenbin Liang, Elizabeth H. Kim, Reza Rafie, Alessandro Giacomello, Eduardo Marbán, Hee Cheol Cho   +6 more
doaj   +1 more source

Translating Biomedical Research to Medical Devices: A Practical Guide and the Arteriovenous Graft Case Study

Advanced NanoBiomed Research, EarlyView.
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani, Nina Bono, Alice Caldiroli, Stefania Adele Riboldi, Gabriele Candiani   +4 more
wiley   +1 more source

Peculiarities of uretral pacemaker zones innervation

Бюллетень сибирской медицины, 2009
Peculiarities of extra-intraorgan innervation of uretral pacemaker zones (upper and lower urethral narrowings) were investigated. Anatomic-histological investigation results showed that upper (the I order pacemaker) and middle (the II order pacemaker ...
A. I. Tsukanov, V. F. Baitinger
doaj   +1 more source

Left Ventricular Outflow Tract Geometry as a Predictor of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation Using the Evolut Series

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Predicting the need for permanent pacemaker implantation (PPM) after transcatheter aortic valve implantation (TAVI) is crucial for procedural planning and patient counseling. Aims To evaluate whether left ventricular outflow tract (LVOT) morphology, specifically a tapered configuration, predicts conduction disturbances requiring PPM
Mahmoud Abdelshafy, Angela McInerney, Ahmed Elmeanawy, Paolo Alberto Del Sole, Max Wagener, Hatem Helal, Mahmoud Abozaid, Ashraf Alamir, Tamer Fouad, Alsayed Almarghany, Briain MacNeill, Osama Soliman, Darren Mylotte, Mohammad Abdelghani   +13 more
wiley   +1 more source

پیش‌بینی قابلیت القای تاکی‌کاردی بطنی بر اساس قابلیت هدایت بطن به دهلیز در بیماران مشکوک به تاکی‌آریتمی بطنی

مجله دانشکده پزشکی اصفهان, 2010
مقدمه: امکان پیش‌بینی قابلیت القای تاکی‌کاردی بطنی از طریق فاکتورهای بالینی و نیز قابلیت هدایت بطن به دهلیز، شناسایی بیماران پر خطر برای تاکی‌آریتمی بطنی را آسان‌تر می‌کند. روش‌ها: تعداد 54 نفر از مراجعین به درمانگاه‌های بیمارستان چمران اصفهان، که به علت
Mohammad Reza Samiei nasab, Azam Soleimani, Mohammad Reza Dehghani   +2 more
doaj  

TAVR in Male Patients With Large Aortic Valve Annuli: A Propensity‐Matched Analysis of Balloon‐Expandable Versus Self‐Expanding Valves

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Trans‐catheter aortic valve replacement (TAVR) in patients with large annuli poses procedural difficulties and possible complications. Aims We sought to compare the peri‐procedural and long‐term outcomes of patients with large annuli undergoing TAVR with self‐expanding (SEV) versus balloon‐expandable (BEV) valves.
Lior Zornitzki, Itamar Loewenstein, Shir Frydman, Maayan Konigstein, Jeremy Ben‐Shoshan, Yaron Arbel, Israel Barbash, Ran Kornowski, Gabby G. Elbaz, Danny Dvir, Ariel Finkelstein, Shmuel Banai, Arie Steinvil   +12 more
wiley   +1 more source