Results 31 to 40 of about 2,588,348 (312)
Ecosystems services research in action: reflexively valuing environments in the South Pacific
Ecology and Society, 2021 Ecosystem services (ES) are heralded as an approach that communicates across disciplines and between researchers and resource managers, encouraging more environmentally sustainable human behavior.
Chelsea E. Hunter, Matthew Lauer
doaj +1 more source
A Profile of Pacific Islanders in Oakland, California [PDF]
, 2007 Pacific Islanders represent less than one percent of Oakland's population and as a result may be overlooked or categorized with other disparate communities.
Lila K. Booth
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Creating Jobs in Samoa Through Public-Private Partnerships [PDF]
, 2016 Samoa’s achievement in contracting out to the private sector the functions of its Public Works Department (PWD) is one of the most successful reforms to upgrade infrastructure; improve the effectiveness of public expenditure; and increase the overall ...
Pacific Private Sector Development Initiative
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The Politics of Invisibility: Visualizing Legacies of Nuclear Imperialisms
Journal of Transnational American Studies, 2020 Questions of visibility, witnessing, and agency are particularly pertinent to post-1945 US and French nuclear testing across Oceania. Images of enormous hovering atomic mushroom clouds have become familiar icons of this testing, while images of the ...
Fiona Amundsen, Sylvia C. Frain
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Learning as spirituality and nurture - Pacific indigenous peoples' perspectives of lifelong learning [PDF]
, 2012 This paper discusses characteristics of an adult education practice for peoples in the Pacific. There is no one Pacific way as the Pacific population is diverse consisting of many cultures, languages, social structures and differing colonial experiences.
Vaioleti, Timote Masima
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Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih +40 more
wiley +1 more source