Results 71 to 80 of about 419,720 (266)
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin +16 more
wiley +1 more source
New observations on the resistance of coconut cultivars to tropical cyclones in Vanuatu
The resistance of coconut palms to violent winds was observed at the Saraoutou research station as cyclone Dani passed over the island of Santo in Vanuatu in January 1999.
Jean-Pierre LABOUISSE +2 more
doaj +1 more source
Conventional passive radiative cooling films rely on costly feedstocks and energy‐intensive fabrication, with poor end‐of‐life compatibility in agriculture. To address this challenge, a sustainable radiative cooling mulch (SRCM) is developed from waste maize leaves via spontaneous hydrogen‐bond self‐assembly.
Hao Li +13 more
wiley +1 more source
CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors
Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen +12 more
wiley +1 more source
Popular Political Attitudes in Vanuatu: Findings of the Pacific Attitudes Survey
This paper presents the findings of the second Pacific Attitudes Survey (PAS), conducted in Vanuatu from August–October 2023. Drawing on a nationally representative sample (n = 1330) of ni‐Vanuatu of voting‐age (18+), the PAS gauges the views of ordinary
Christopher Mudaliar +6 more
doaj +1 more source
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak +6 more
wiley +1 more source
Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates
Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao +4 more
wiley +1 more source
Book review Sea Sisters: Un équipage féminin à l‘épreuve de la pollution dans le Pacifique. (Le Roux, G. 2021) [PDF]
Fache, Elodie
doaj +1 more source
Continuous wet‐spinning of PANI with TeNWs yields a multifunctional microfiber. Oriented TeNWs impose chain alignment and enhance π‐electron delocalization, boosting the Seebeck coefficient to 59.9 µV K−1 for passive temperature sensing (1 K detection limit), while achieving high pH sensitivity (59.25 mV pH−1) and rapid NH3 response (0.96 s).
Dongmei Xie +10 more
wiley +1 more source

