TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Longitudinal Association of Maternity Care Practices with Exclusive Breastfeeding in U.S. Hospitals, 2018-2022. [PDF]
Children (Basel)Gosdin L +6 more
europepmc +1 more source
Abstract Representation of Movement Parameters in Basal Ganglia Output
Advanced Science, EarlyView.The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero +3 more
wiley +1 more source
Microbial contamination of medicines, medical devices, cosmetics, child and personal care products: a comprehensive review of secondary contamination risks in home-use settings. [PDF]
Front MicrobiolIskandar K, Marchin L, Roques C.
europepmc +1 more source
Advanced Science, EarlyView.Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen +10 more
wiley +1 more source
Sensory Saturation (3T) for Pain Management During ROP Screening in Preterm Infants Born Between 32 to 36 Weeks of Gestational Age. [PDF]
J OphthalmolNi Y, Zhao X, Xu J, Zhou C.
europepmc +1 more source
Advanced Science, EarlyView.Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo +11 more
wiley +1 more source
Oral Health Promotion in Pediatric Age Groups: Habits and Behaviors of Italian and Spanish Parents and Children. [PDF]
J Clin MedMariotti F +6 more
europepmc +1 more source
Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content
Advanced Science, EarlyView.Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri +3 more
wiley +1 more source
LATCH score and 6-month exclusive breastfeeding in a Baby-Friendly Hospital. [PDF]
Rev Assoc Med Bras (1992)Dursun HK +4 more
europepmc +1 more source