Results 101 to 110 of about 26,415 (315)
Advanced Science, EarlyView.The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo +14 more
wiley +1 more source
Cogent Arts & Humanities, 2015 War chariots and armoured beasts of war played a major role in wars and influenced the outcomes of battles. The industrial era and age of total war saw new transmutations of this tool of war.
Ian Liebenberg
doaj +1 more source
The princess at the conference: Science, pacifism, and Habsburg society. [PDF]
Hist Sci, 2021 Somsen G.
europepmc +1 more source
Risk-transfer militarism, small massacres and the historic legitimacy of war [PDF]
, 2002 The perception of initial success in the `war against terrorism' appears to strengthen a general relegitimation of war in Western society that has been gathering pace over the last two decades.
Shaw, Martin
core +2 more sources
Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems
Advanced Science, EarlyView.Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen +8 more
wiley +1 more source
Un educador ‘menor’ antes de Comenius: el pacifismo de Petr Chelčický
Acta Scientiarum. Education, 2015 Este artículo trata de Petr Chelčický, que vivió en Bohemia en la primera mitad del siglo XV. En un ejercicio historiográfico de observar el lugar dado a este sujeto en la historia de las religiones, el texto propone re(construir) su lugar en la historia
Thiago Borges de Aguiar
doaj +1 more source
John Diamond Did Not Battle Cancer Bravely. [PDF]
Br J Gen Pract, 2022 Lawson E.
europepmc +1 more source
The Complex Hybridity of Ham Sok-Heon
, 2017 This paper examines the multiple elements of Korean Quaker Ham Sok-Heon’s religious, political, and theological identity from the perspective of hybridity, with a special focus on the impact of that hybridity on Quaker reconciliation theology.
Randazzo, Dan Christy
core
Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
Advanced Science, EarlyView.The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li +10 more
wiley +1 more source
Advanced Science, EarlyView.The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob +12 more
wiley +1 more source