Results 161 to 170 of about 118,730 (317)

Continuous Evolution System Based on Toxin–Antitoxin System Combined with Base Deaminase Accelerates the In Vivo Modification of Target Proteins

Advanced Science, EarlyView.
The promoted Escherichia coli‐assisted continuous evolution (PEACE) system operates through a stringent three step genetic circuit: target gene mutation via a deaminase–T7 RNA polymerase (T7 RNAP) fusion, coupling variant function to antitoxin expression, and growth based selection of surviving cells.
Xinyu Zhang, Zhanzhi Liu, Ying Xu, Mingjing Sun, Guangzhen Zhou, Deming Rao, Xiaoqian Chen, Sheng Wang, Zhigang Li, Yan Huang, Jing Wu   +10 more
wiley   +1 more source

Suppression of Paroxysmal Atrial Fibrillation by Pacing

, 2003
Atrial Fibrillation (AF) affects approximately five million people world- wide. The incidence of AF increases with aging and more common in males.1 Atrial fibrillation is the most common cardiogenic cause of stroke and exacerbates heart failure.
Gupta, Anoop K., Anoop K. Gupta
core  

Left Bundle Branch Area Pacing as a Rescue Strategy After Failed Cardiac Resynchronization Therapy in a Patient With Persistent Left Superior Vena Cava, Absent Coronary Sinus Branches, After Bilateral Maze Procedure: A Case Report. [PDF]

Am J Case Rep
Kohoutková L, Augustynek M, Šipula D.
europepmc   +1 more source

Electrochemically Driven Regioselective Radical Functionalization of Allenes: Scope and Mechanistic Insights

Advanced Science, EarlyView.
Allenes emerge as powerful platforms for electrochemical functionalization through radical pathways. Selective radical addition at the central carbon triggers anodic oxidation and intramolecular cyclization, enabling efficient synthesis of oxazolines and oxazolidine‐2‐imines without external oxidants.
Pranjal Pyne, Prateek Saini, Rohel Hoque, Shivam Pandey, Srinivasan Ramakrishnan, Chandra M. R. Volla   +5 more
wiley   +1 more source

Change of Atrial Refractory Period after Short Duration of Rapid Atrial Pacing: Regional Differences and Possible Mechanisms

, 2009
It is unknown whether there are regional differences in the change of atrial effective refractory period (ERP) after a short duration of rapid atrial pacing.
林芳郁, LEE, SHIH-HUANG; CHEN, SHIH-ANN; YU, WEN-CHUNG; CHENG, JUN-JAGK; KAUN, PEILIANG; HUNG, GHI-REN; CHANG, MAU-SONG; LIN, FANG-YUE   +1 more
core  

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

DDDR versus DDD and VVIR pacing: A single blind randomised evaluation of symptoms and effort performance

, 1993
The aim of this study was to evaluate effort performance and subjective symptoms in a within-patient comparison of DDDR, DDD and VVIR pacing. A DDDR pacemaker (Synergyst II, Medtronic) was implanted in 14 patients (mean age 66.5 ± 5.0 yrs.) with sick ...
Boriani, G., Piccolo, E., Capucci, A., Zanuttini, D., Cazzin, R., Zardo, F.   +5 more
core  

Permanent Cardiac Pacing in Children: A 30-Year Follow-Up Retrospective Study in a Single Pediatric Asian Center. [PDF]

J Arrhythm
Chan JC, Zhang DZ, Xuan KZ, Sundararaghavan S, Choo JTL, Ho KL, Lim ETS, Tan JL, Aziz NBA, Chan WT, Kotecha M, Lee JH, Tan TH.   +12 more
europepmc   +1 more source

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

Advanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu, Fangting Ma, Fan Ding, Luyan Wang, Yunxi Li, Yunzhi He, Xingang Zhang, Siyu He, Dandan Liu   +8 more
wiley   +1 more source

Pacing for Vasovagal Syncope

, 2002
Vasovagal syncope is a common condition, usually associated with a benign prognosis. Most sufferers experience only occasional symptoms, and can be treated with reassurance and lifestyle advice. However, a minority of patients are debilitated by frequent
Wijesekera, Nevin T, Nevin T Wijesekera, Kurbaan, Arvinder S, Arvinder S Kurbaan   +3 more
core