Results 61 to 70 of about 83,142 (315)

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Poseidon: Mitigating Interest Flooding DDoS Attacks in Named Data Networking [PDF]

, 2013
Content-Centric Networking (CCN) is an emerging networking paradigm being considered as a possible replacement for the current IP-based host-centric Internet infrastructure. In CCN, named content becomes a first-class entity.
Compagno, Alberto, Conti, Mauro, Gasti, Paolo, Tsudik, Gene   +3 more
core   +3 more sources

Tuple space explosion: a denial-of-service attack against a software packet classifier

Conference on Emerging Network Experiment and Technology, 2019
Efficient and highly available packet classification is fundamental for various security primitives. In this paper, we evaluate whether the de facto Tuple Space Search (TSS) packet classification algorithm used in popular software networking stacks such ...
Levente Csikor, Dinil Mon Divakaran, M. Kang, Attila Korösi, Balázs Sonkoly, Dávid Haja, D. Pezaros, S. Schmid, G. Rétvári   +8 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Detection and Prevention of Selective Forwarding-Based Denial-of-Service Attacks in WSNs

International Journal of Distributed Sensor Networks, 2013
Designing wireless sensor networks (WSNs) that can work reliably in the presence of inside packet drop attackers is very challenging. Current trust mechanisms and avoidance approaches are promising but have their limitations.
Youngho Cho, Gang Qu
doaj   +1 more source

Ieaack-Secure Detection System For Packet-Dropping Attack In Manets

, 2015
MANET is a collection of wireless independent nodes along with transmitter and receiver that communicate with each other via bidirectional link. The self-configuring ability of nodes in MANET made it popular among critical mission applic ations like military use or emergency recovery.
Prof. Abhijit. V. Mophare,, Prof. Amarnath Shivanand Chadchankar   +1 more
openaire   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Sleep Deprivation Attack Detection in Wireless Sensor Network

, 2012
Deployment of sensor network in hostile environment makes it mainly vulnerable to battery drainage attacks because it is impossible to recharge or replace the battery power of sensor nodes.
Bhattasali, Tapalina, Chaki, Rituparna, Sanyal, Sugata   +2 more
core   +3 more sources

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia, Stephane Rodriguez, Emilie Dugast, Christine Lebrun‐Frenay, Eric Thouvenot, Jérôme de Sèze, Emmanuelle Le Page, Sandra Vukusic, Inès Doghri, Eric Berger, Olivier Casez, Pierre Labauge, Aurélie Ruet, Catarina Raposo, Fabienne Le Frère, Arnaud B. Nicot, Sandrine Wiertlewski, Pierre‐Antoine Gourraud, Laure Michel, Laureline Berthelot, David‐Axel Laplaud   +20 more
wiley   +1 more source

Moving target defense against network eavesdropping attack using POF

Tongxin xuebao, 2018
Eavesdropping attack hereby was the major attack for traditional network communication.As this kind of attacks was stealthy and untraceable,it was barely detectable for those feature detection or static configuration based passive defense approaches ...
Duohe MA, Qiong LI, Dongdai LIN
doaj   +2 more sources