Results 31 to 40 of about 81,484 (234)

Fast tunable lasers in radio-over-fiber access networks [PDF]

, 2006
The authors present a novel concept of employing optical wavelength packet switching (WPS) in radio-over-fiber (RoF) access networks. The Central Station is equipped with a fast tunable laser (TL), which is externally modulated with a data signal ...
Barry, Liam P., Connolly, Eoin M., Kaszubowska-Anandarajah, Aleksandra, McDonald, David   +3 more
core   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Mind the gap: void-creating algorithms for optical switching [PDF]

, 2015
With ever-increasing demand for bandwidth, optical packet/burst switching is proposed to utilize more of the available capacity of optical networks in the future.
Bruneel, Herwig, Rogiest, Wouter, Van Hautegem, Kurt   +2 more
core   +1 more source

Architecture, design, and modeling of the OPSnet asynchronous optical packet switching node [PDF]

, 2005
An all-optical packet-switched network supporting multiple services represents a long-term goal for network operators and service providers alike.
Harle, D.A., Vanderbauwhede, W.A.
core   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Performance assessment of optical packet switching system with burst-mode receivers for intra-data centre networks [PDF]

, 2014
We investigate the performance of a burst-mode receiver in an optical packet switching system. Experimental results indicate that a preamble of 25.6ns allows error-free operation of 10Gb/s asynchronous switched packets with 8dB dynamic range and 25ns ...
Bauwelinck, Johan, Calabretta, Nicola, Dorren, Harm, Miao, Wang, Yin, Xin   +4 more
core   +2 more sources

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

Advanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard, Kaja Borup Løvschall, Mireia Casanovas Montasell, Clara Bakkegaard Cramer, Pere Monge Marcet, Andreas Bøtker Pedersen, Josefine Hammer Jakobsen, Alexander N. Zelikin   +7 more
wiley   +1 more source

Light‐Triggered Protease‐Mediated Release of Actin‐Bound Cargo from Synthetic Cells

Advanced Biology, EarlyView.
TEV Prtoease‐mediated Releasable Actin‐binding Protein (TRAP) is a protein‐based platform consisting of a cargo tightly bound to reconstituted actin networks in synthetic cells which can be proteolyticly released from the bound actin, followed by its secretion through membrane translocation mediated by a cell‐penetrating peptide.
Mousumi Akter, Hossein Moghimianavval, Gary D. Luker, Allen P. Liu   +3 more
wiley   +1 more source

Impact of topology on layer 2 switched QoS sensitive services [PDF]

, 2010
High-bandwidth QoS sensitive services such as large scale video surveillance generally depend on provisioned capacity delivered by circuit-switched technology such as SONET/SDH.
Colle, Didier, Demeester, Piet, Michielsen, Jurgen, Moeskops, Marc, Pickavet, Mario, Puype, Bart, Tavernier, Wouter, Verbanck, Geert   +7 more
core   +2 more sources

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source