Results 41 to 50 of about 1,611,065 (368)

Survey of unified approaches to integrated-service networks [PDF]

open access: yes, 1989
The increasing demand for communication services, coupled with recent technological advances in communication media and switching techniques, has resulted in a proliferation of new and expanded services.
Bradley, Tracy T., Suda, Tatsuya
core  

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Characterization of wavelength tunable lasers for future optical communication systems [PDF]

open access: yes, 2010
The use of tunable lasers (TL) in dense wavelength division multiplexed (DWDM) networks for optical switching, routing and networking has gained a lot of interest in recent years.
Anandarajah, Prince M.   +4 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Optimization Strategy to Solve Transmission Interruption Caused by Satellite-Ground Link Switching

open access: yesIEEE Access, 2020
Low earth orbit (LEO) satellite systems, an important part of the next generation of global communication systems, have the advantages of low transmission delay, low satellite cost and low launch cost.
Jirui Zhang   +3 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Demonstration of an SDM Network Testbed for Joint Spatial Circuit and Packet Switching †

open access: yesPhotonics, 2018
We demonstrate a spatial division multiplexing (SDM) network testbed composed of three nodes connected via 19-core multi-core fibers. Each node is capable of joint spatial circuit switching and joint packet switching to support 10 Tb/s spatial circuit ...
Ruben S. Luis   +4 more
doaj   +1 more source

Multi-Granular Optical Cross-Connect: Design, Analysis, and Demonstration [PDF]

open access: yes, 2009
A fundamental issue in all-optical switching is to offer efficient and cost-effective transport services for a wide range of bandwidth granularities. This paper presents multi-granular optical cross-connect (MG-OXC) architectures that combine slow (ms ...
Bart Dhoedt   +25 more
core   +3 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Network traffic behaviour near phase transition point [PDF]

open access: yes, 2005
We explore packet traffic dynamics in a data network model near phase transition point from free flow to congestion. The model of data network is an abstraction of the Network Layer of the OSI (Open Systems Interconnection) Reference Model of packet ...
Lawniczak, Anna T., Tang, Xiongwen
core   +2 more sources

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