Results 51 to 60 of about 1,611,065 (368)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Retrial Queuing Models of Multi-Wavelength FDL Feedback Optical Buffers [PDF]

open access: yes, 2011
Cataloged from PDF version of article.Optical buffers based on Fiber Delay Lines (FDL) have been proposed for contention resolution in optical packet/burst switching systems.
Akar, N., Sohraby, K.
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Performance evaluation of the multiple output queueing switch with different buffer arrangements strategy

open access: yesJournal of Telecommunications and Information Technology, 2006
Performance evaluation of the multiple output queueing (MOQ) switch recently proposed by us is discussed in this paper. In the MOQ switch both the switch fabric and buffers can operate at the same speed as input and output ports.
Grzegorz Danilewicz   +2 more
doaj   +1 more source

Stroboscopic wave-packet description of nonequilibrium many-electron problems [PDF]

open access: yes, 2008
We introduce the construction of an orthogonal wave-packet basis set, using the concept of stroboscopic time propagation, tailored to the efficient description of nonequilibrium extended electronic systems.
Bokes, P., Corsetti, F., Godby, R. W.
core   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Full‐range wavelength switching at tunable distributed amplification‐DFB laser with high‐accuracy feedforward control

open access: yesElectronics Letters, 2021
To realise an optical packet switching system, a tunable laser that can achieve high‐speed and wide‐range tuning is required. One candidate, we have studied for this role, is the tunable distributed amplification (TDA)‐distributed feedback (DFB) laser ...
Yuri Niiya   +2 more
doaj   +1 more source

NaI revisited: Theoretical investigation of predissociation via ultrafast XUV transient absorption spectroscopy. [PDF]

open access: yes, 2019
Avoided crossings can trigger abrupt changes of electronic character and redirect the outcomes of photochemical reactions. Here, we report a theoretical investigation into core-level spectroscopic probing of predissociation dynamics of sodium iodide (NaI)
Kobayashi, Yuki   +3 more
core   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Integrated 1 $\times$ 8 Optical Phased-Array Switch With Low Polarization Sensitivity for Broadband Optical Packet Switching

open access: yesIEEE Photonics Journal, 2009
An InP/InGaAsP integrated 1 times 8 optical phased-array switch is designed, fabricated, and characterized for high-throughput broadband wavelength-division multiplexed (WDM) optical packet switching application.
Ibrahim Murat Soganci   +2 more
doaj   +1 more source

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