Results 101 to 110 of about 1,002,043 (319)
Generation of Optimal Packings from Optimal Packings [PDF]
We define two notions of generation between the various optimal packings ${\cal Q}_m^K$ of $m$ congruent disks in a subset $K$ of ${\Bbb R}^2$. The first one that we call weak generation consists in getting ${\cal Q}_n^K$ by removing $m-n$ disks from ${\cal Q}_m^K$ and by displacing the $n $ remaining congruent disks which grow continuously and do not ...
openaire +2 more sources
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
THE PACKING SIMULATION MODEL [PDF]
The Packing Simulation Model is a microcomputer application program designed for researchers, extension personnel, bankers, packing managers, or other specialists who plan the operations of a packing facility or simulate its financial performance ...
Falk, Constance L. +2 more
core +1 more source
Protocol dependence of the jamming transition
We propose a theoretical framework for predicting the protocol dependence of the jamming transition for frictionless spherical particles that interact via purely repulsive contact forces. We study isostatic jammed disk packings obtained via two protocols:
Behringer, R. P. +4 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Subdivision into i-packings and S-packing chromatic number of some lattices [PDF]
An $i$-packing in a graph $G$ is a set of vertices at pairwise distance greater than $i$. For a nondecreasing sequence of integers $S=(s\_{1},s\_{2},\ldots)$, the $S$-packing chromatic number of a graph $G$ is the least integer $k$ such that there exists
Gastineau, Nicolas +2 more
core +2 more sources
Dense crystalline dimer packings of regular tetrahedra
We present the densest known packing of regular tetrahedra with density phi = 4000/4671 = 0.856347... Like the recently discovered packings of Kallus et al.
Chen, Elizabeth R. +2 more
core +1 more source

