Results 201 to 210 of about 561,323 (357)

Effect of Velocity Alignment on the Packing of Active Particles. [PDF]

Micromachines (Basel)
Modi J, Jin R, Dong K, Fang G.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Enhanced CO₂ conversion <i>via</i> synergistic effect of dielectric barrier discharge plasma and halogen-modified g-C₃N₄. [PDF]

RSC Adv
Rao MU, Cho PP, Vidyasagar D, Joseph S, Patel S, Chang-Chien GP, Masimukku S, Madras G, Subrahmanyam C.   +8 more
europepmc   +1 more source

The influence of cell mechanics, cell-cell interactions, and proliferation on epithelial packing.

Current Biology, 2007
Reza Farhadifar, Jens-Christian Röper, B. Aigouy, S. Eaton, F. Jülicher   +4 more
semanticscholar   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States. [PDF]

Adv Sci (Weinh)
Dunton CL, Paola Gonzalez C, Almassalha L, Li WS, Gong R, Acosta N, Ye IC, Frederick J, Hogg C, John S, Williams JAG, Nap RJ, Szleifer I, Backman V.   +13 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Supramolecular Behaviour of Heterochiral Dipeptides With Ile. [PDF]

J Pept Sci
Scarel E, Alletto P, Adorinni S, Fazio F, Pierri G, Tedesco C, Marchesan S.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Steric Control of Molecular Packing Governs Excimer Emission in Fluorene-Based Molecular Solids. [PDF]

Chem Mater
Cunha C, Paixão JA, Seixas de Melo JS.
europepmc   +1 more source