Structural Insights Into Amyloid Polymorphism: The Impact of Glutamine to Norleucine Substitutions in GNNQQNY Aggregation. [PDF]
Bencs F +3 more
europepmc +1 more source
Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt +2 more
wiley +1 more source
Conserved function of the HAUS6 calponin homology domain in anchoring augmin for microtubule branching. [PDF]
Würtz M +13 more
europepmc +1 more source
Band Alignment in In‐Oxo Metal Porphyrin SURMOF Heterojunctions
Porphyrin core metalation in indium‑oxo SURMOFs enables systematic tuning of band edge positions without altering the crystal structure. First‑principles calculations reveal type‑I and type‑II heterostructures as well as multi‑junction energy cascades, establishing a modular strategy for exciton funneling and charge separation in optoelectronic ...
Puja Singhvi, Nina Vankova, Thomas Heine
wiley +1 more source
Optimizing a coarse-grained model for large-scale membrane protein simulation. [PDF]
Wen CY, Luo YL, Madsen JJ.
europepmc +1 more source
Unleashing the Power of Machine Learning in Nanomedicine Formulation Development
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore +7 more
wiley +1 more source
Synthesis of crystalline polyamide for synergistically strengthening anticorrelated mechanical property and high-temperature capacitive energy storage. [PDF]
Fan K +8 more
europepmc +1 more source
This study advances our understanding of aortic valve stenosis by capturing spatially resolved chemical and structural changes at the nanoscale. The findings highlight the potential of combined Raman and electron microscopy for understanding calcification mechanisms across diverse tissue types.
Robin H. M. Van der Meijden +11 more
wiley +1 more source
Structural Analysis of Missense Mutations on the Stability of APOE3 and APOE4. [PDF]
Anthony M, Xie Y, O'Neil JN, Teng S.
europepmc +1 more source

