Results 211 to 220 of about 58,816 (267)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Intramolecular Charge-Transfer Dopants Enable Isolated Triplet Excitons as Spin Qutrits in a Single Crystal. [PDF]

open access: yesAngew Chem Int Ed Engl
Han Y   +6 more
europepmc   +1 more source

How Viscoelastic Effects Impact Polymer Fluid Flow in Porous Media. [PDF]

open access: yesTransp Porous Media
Wang Y   +5 more
europepmc   +1 more source

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