Results 61 to 70 of about 331,594 (334)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A comparative study of postoperative airway management between traditional nasal packing and modified nasal airway after nasal surgeries

Journal of University Medical & Dental College, 2022
BACKGROUND & OBJECTIVE: One of the most common challenging complications after nasal surgeries is maintaining airways. The study aimed to use an alternative technique instead of nasal packing in the immediate postoperative period undergoing different ...
Muhammad Saleem, Baber Rafiq Khan, Sarwat Bibi, Humaira Ahmad, Muhammad Hamza Rana   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Complex continued fractions with restricted entries

Electronic Journal of Differential Equations, 1998
We study special infinite iterated function systems derived from complex continued fraction expansions with restricted entries. We focus our attention on the corresponding limit set whose Hausdorff dimension will be denoted by $h$. Our primary goal is to
Pawel Hanus, Mariusz Urbanski
doaj  

Multiscaling at Point J: Jamming is a Critical Phenomenon

, 2005
We analyze the jamming transition that occurs as a function of increasing packing density in a disordered two-dimensional assembly of disks at zero temperature for ``Point J'' of the recently proposed jamming phase diagram. We measure the total number of
C. J. Olson Reichhardt, C. Reichhardt, I. M. Lifshitz, J. A. Drocco, M. B. Hastings   +4 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Hausdorff and packing dimensions of the images of random fields

, 2010
Let $X=\{X(t),t\in\mathbb{R}^N\}$ be a random field with values in $\mathbb{R}^d$. For any finite Borel measure $\mu$ and analytic set $E\subset\mathbb{R}^N$, the Hausdorff and packing dimensions of the image measure $\mu_X$ and image set $X(E)$ are ...
Shieh, Narn-Rueih, Xiao, Yimin
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Multifractal Structure of Irregular Sets via Weighted Random Sequences

Fractal and Fractional
We study the multifractal structure of irregular sets arising from Fibonacci-weighted sums of sequences of random variables. Focusing on Cantor-type subsets Kε of the unit interval, we construct sequences of free and forced blocks, where the free blocks ...
Najmeddine Attia, Taoufik Moulahi
doaj   +1 more source

Evaluation of the k_La_e of Structured Packings in Small Diameter Columns - The Key Role of Wall-Wipers

Chemical Engineering Transactions, 2018
Wall wipers are commonly used in columns filled with structured packings in order to reduce the liquid flow along the column walls. In small diameter columns wall regions are prominent and wall flow, if not well tended to, can adversely affect measured ...
John Roesler, Pascal Alix, Aude Royon-Lebeaud, Lukas Valenz, Jan Haidl, Frantisek Rejl   +5 more
doaj   +1 more source