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Pharmacogenetics of paclitaxel metabolism
Critical Reviews in Oncology/Hematology, 2007Paclitaxel is one of the most widely used and effective anticancer drugs. Paclitaxel's clinical utility spans many tumor sites, including treatment of ovarian, breast, lung, head and neck, and unknown primary cancers. As is the case with most chemotherapy drugs, paclitaxel is administered empirically with little individualization of dose other than ...
Jennifer L. Spratlin, Michael B. Sawyer
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A facile N-debenzoylation of paclitaxel: Conversion of paclitaxel to docetaxel
Tetrahedron Letters, 1999AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Prakash Jagtap, David G. I. Kingston
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Pharmacology and Pharmacokinetics of Paclitaxel
Annals of Pharmacotherapy, 1994There remain several pharmacologic considerations relating to paclitaxel that are being, or need to be, explored. Some of the more important of these include the following issues: Further elaboration of the metabolic fate of paclitaxel. A multicenter study is currently being planned to determine the complete metabolic fate of paclitaxel, using ...
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