Results 251 to 260 of about 281,052 (341)

Paclitaxel, interferons and functional reprogramming of tumor-associated macrophages in optimized chemo-immunotherapy. [PDF]

J Immunother Cancer
Kalinski P, Kokolus KM, Gandhi S.
europepmc   +1 more source

Paclitaxel and tamoxifen

, 2000
Faith E. Nathan, David Berd, Takami Sato, Michael J. Mastrangelo   +3 more
openalex   +1 more source

Targeted reactivation of the novel tumor suppressor DAPK1, an upstream regulator of p53, in high‐grade serous ovarian cancer by mRNA liposomes reduces viability and enhances drug sensitivity in preclinical models

Cancer Communications, EarlyView.
Monika Raab, Balázs Győrffy, Samuel Peña‐Llopis, Daniela Fietz, Monika Kressin, Margareta Kolaric, Matthias Ebert, Khayal Gasimli, Sven Becker, Mourad Sanhaji, Klaus Strebhardt   +10 more
wiley   +1 more source

C13‐Deacylase from Nocardioides albus Resp. Streptomyces sp., Catalyzing Side Chain Hydrolysis on the Taxane Core

ChemCatChem, EarlyView.
An enzyme that has been identified and characterized as capable of hydrolyzing paclitaxel (Taxol), a key anticancer drug derived from Pacific yew (Taxus brevifolia) has been identified. Molecular docking (MD) simulations map the catalytic triad and critical residues that drive substrate‐enzyme interactions. The findings indicate the catalytic potential
Jinfen Su, Eugen Schell, Thomas Heine, Marion B. Ansorge‐Schumacher   +3 more
wiley   +1 more source

The clinical potentials of combining paclitaxel-based chemotherapy regimen with metformin in cancer treatment: A systematic review and Meta-analysis. [PDF]

Transl Oncol
Omidi Sarajar B, Rastegar-Pouyani N, Rasouli A, Nikbakht F, Nezami Majd M, Ghahremani MH, Ostad SN, Jafarzadeh E, Dehghani M.   +8 more
europepmc   +1 more source

Paclitaxel plus vinorelbine: An active regimen in metastatic breast cancer patients with prior anthracycline exposure

, 2000
M. Martín, Aña Lluch, Antonio Casado, Iciar Garcı́a Carbonero, Lucía Paz, Carmen Esteban, Amelia Insa, Rosario Alfonso, J Garcı́a-Conde, Eduardo Díaz‐Rubio   +9 more
openalex   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

Emerging Trends in the Application of Nanosuspension-Based Biomaterials for Anticancer Drug Delivery. [PDF]

Int J Nanomedicine
Aldeeb MME, Wilar G, Suhandi C, Mohammed AFA, Mahmoud SA, Elamin KM, Wathoni N.   +6 more
europepmc   +1 more source

Surface Wipe Sampling of Hazardous Medicinal Products: A European Interlaboratory Comparison Study

Drug Testing and Analysis, EarlyView.
This study aimed to conduct an interlaboratory comparison (ILC) program to evaluate the performance of European laboratories in detecting hazardous medicinal products (HMPs) from surface wipe samples, using their own sampling and analytical methods.
Roland B. van den Berg, Ewelina Korczowska, Mónica S. F. Santos, Maria Francisca Portilha‐Cunha, Ana R. L. Ribeiro, Lucie Bláhová, Luděk Bláha, Claudia Vom Eyser, Jochen Tuerk, Richard C. J. M. van Rossen, Erik B. Wilms, Mirjam Crul   +11 more
wiley   +1 more source

A novel taxane SB-T-101141 triggers a noncanonical ferroptosis to overcome Paclitaxel resistance of breast cancer via iron homeostasis-related KHSRP. [PDF]

Cell Death Dis
Zhang X, Fang Y, Rong D, Li J, Li Z, Qiu H, Chen Q, Yang J, Wang C, Huang J, Zhao Q, Yang S, Wang H.   +12 more
europepmc   +1 more source