The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary
ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley +1 more source
Developing an adaptive paediatric intensive care unit platform trial with key stakeholders: a qualitative study. [PDF]
Mitchell TK +12 more
europepmc +1 more source
Autism Spectrum Disorder Among Gender‐Diverse Children and Adolescents: A National Cohort Study
ABSTRACT Autism spectrum disorder (ASD) is more prevalent in transgender and gender‐diverse (TGD) individuals than in the general population, yet the specific developmental pathways within and clinical outcomes of this intersection are insufficiently understood.
Erez Topaz +7 more
wiley +1 more source
Response to the Letter to the Editor Titled "A Possible Alternative in the Treatment of Obstructive Airway Disease in Paediatric Intensive Care Patients". [PDF]
Kocaoglu Barlas U.
europepmc +1 more source
Paediatric intensive care: challenges and promise
Stephen, Jacobe +2 more
openaire +2 more sources
ABSTRACT Objective behavioral assessments for autism spectrum disorder (ASD) are often time‐intensive and require substantial clinical expertise. Eye‐tracking–based paradigms offer quantifiable measures of social attention that can complement traditional tools.
Fouad Al Shaban +4 more
wiley +1 more source
Interventions to Support Psychological Health Outcomes for Children and Families Experiencing Paediatric Intensive Care Unit (PICU) Admission: A Scoping Review. [PDF]
Scott G +6 more
europepmc +1 more source
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki +3 more
wiley +1 more source
Transition from neonatal to paediatric intensive care of very preterm-born children: a cohort study of children born between 2013 and 2018 in England and Wales. [PDF]
van Hasselt TJ +8 more
europepmc +1 more source
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun +4 more
wiley +1 more source

