Results 221 to 230 of about 123,268 (305)

Universal administration of nirsevimab in infants: an analysis of hospitalisations and paediatric intensive care unit admissions for RSV-associated lower respiratory tract infections. [PDF]

Eur J Pediatr
Bermúdez-Barrezueta L, Matías Del Pozo V, Marugán-Miguelsanz JM, López EI, Uribe-Reina P, Romero Del Hombrebueno Y, Morales-Moreno AJ, Rojo-Rello S, Eiros JM, Pino-Vázquez MA.   +9 more
europepmc   +1 more source

Economic evaluation of the role of telemedicine in paediatric cardiology: Final Report [PDF]

, 2005
Dowie, R, Mistry, H, Weatherburn, G, Young, T   +3 more
core  

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Association between serum procalcitonin levels and outcomes of patients admitted to two tertiary paediatric intensive care units in Bloemfontein: A retrospective analytical study. [PDF]

South Afr J Crit Care
Luyo Sanchez AM, Pienaar MA.
europepmc   +1 more source

Understanding the influence of transfusion and blood loss on tranexamic acid concentration in scoliosis surgery with blood loss

British Journal of Clinical Pharmacology, EarlyView.
Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá, Luisa Barreiros, Marcela A. Segundo, Eugénia Cruz, Sibylle Langenecker   +4 more
wiley   +1 more source

An open abdomen is not a contraindication for ECMO in children with cancer

EJC Paediatric Oncology
Andrea Zühlsdorf, Alexander Humberg, Christoph Zöller, Volker Müller, Andreas Groll, Katja Masjosthusmann, Jenny Potratz   +6 more
doaj   +1 more source

Using experience-based co-design to explore care experiences and identify practice change priorities for children with medical complexity in the paediatric intensive care unit. [PDF]

BMJ Open
Rennick JE, Southall K, Carnevale F, Dryden-Palmer K, Patel H, Dagenais M, Buchanan F, Avery S, Razack S, St-Sauveur I, Cohen E, Fontela P, Law S.   +12 more
europepmc   +1 more source

Low‐intervention clinical trials in Spain: Do they progress?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza, Mayro J. Cortés Pestana, Kristopher Amaro, Rosa M. Antonijoan, Caridad Pontes   +4 more
wiley   +1 more source