Results 241 to 250 of about 123,268 (305)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Predictive model for the risk of paediatric intensive care utilization in children with medical complexity: A longitudinal retrospective cohort study. [PDF]

Nurs Crit Care
Pérez-Ardanaz B, Gutiérrez-Rodríguez L, Gómez-González AJ, Morales-Asencio JM, Montero-García A, León-Campos Á.   +5 more
europepmc   +1 more source

Digital diagnostics, biomarkers and therapeutics in an evolving healthcare system: From promise to practice

British Journal of Clinical Pharmacology, EarlyView.
Abstract Health care is shifting towards a digital‐guided system, integrating digital diagnostics, biomarkers and therapeutics in many care pathways. However, despite rapid technological advancement and preliminary adoption accelerated by the COVID‐19 pandemic, a significant implementation gap persists. This narrative review explores the causes of this
Mees H. P. Stoop, Gertjan J. A. Driessen, Adam F. Cohen, Matthijs D. Kruizinga   +3 more
wiley   +1 more source

AF among Nurses Working in Neonatal and Paediatric Intensive Care Units: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Ali TM, Alharbi MF.
europepmc   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

The elements of end-of-life care provision in paediatric intensive care units: a systematic integrative review. [PDF]

BMC Palliat Care
Adistie F, Neilson S, Shaw KL, Bay B, Efstathiou N.   +4 more
europepmc   +1 more source

Listening to Hong Kong children's perspectives through pretend play

British Educational Research Journal, EarlyView.
Abstract Quality in early childhood education and care (ECEC) has become an increasing concern in recent years. The issue has been regularly discussed by different stakeholders. However, the rising concern regarding quality in ECEC has not seriously taken into account children's perspectives.
Suzannie K. Y. Leung
wiley   +1 more source

Volatile gas scavenging in the paediatric intensive care unit: Occupational health and safety assessment. [PDF]

Can J Respir Ther
Reise K, Macartney J, La R, Jerath A, Slessarev M, Cuthbertson BH, Ganesan SL, McKinnon NK.   +7 more
europepmc   +1 more source

Contribution of ethnicity, area level deprivation and air pollution to paediatric intensive care unit admissions in the United Kingdom 2008-2021. [PDF]

EClinicalMedicine
Mitchell HK, Seaton SE, Leahy C, Mustafa K, Buckley H, Davis P, Feltbower RG, Ramnarayan P.   +7 more
europepmc   +1 more source

Implementation of a structured information transfer checklist improves postoperative data transfer after congenital cardiac surgery [PDF]

, 2013
KARAKAYA, ARIF, Moerman, Anneliese, Peperstraete, Harlinde, Wouters, Patrick   +3 more
core   +1 more source