Results 191 to 200 of about 3,468 (201)

Paeonol attenuates lipopolysaccharide-induced depressive-like behavior in mice

Psychiatry Research, 2016
The present study was designed to detect the anti-depressant effects of paeonol and the possible mechanisms in the lipopolysaccharide-induced depressive-like behavior. Open-field test(OFT), tail suspension test(TST) and forced swimming test(FST) were used to evaluate the behavioral activity. The contents of 5-hydroxytryptamine (5-HT) and norepinephrine
Weiwei, Tao, Hanqing, Wang, Qiang, Su, Yanyan, Chen, Wenda, Xue, Baomei, Xia, Jinao, Duan, Gang, Chen   +7 more
openaire   +2 more sources

Paeonol Derivative, 6′-Methyl Paeonol, Attenuates Aβ-Induced Pathophysiology in Cortical Neurons and in an Alzheimer’s Disease Mice Model

ACS Chemical Neuroscience
Herbs themselves and various herbal medicines are great resources for discovering therapeutic drugs for various diseases, including Alzheimer's disease (AD), one of the common neurodegenerative diseases. Utilizing mouse primary cortical neurons and DiBAC4(3), a voltage-sensitive indicator, we have set up a drug screening system and identified an herbal
Pin-Jung Chen, Chien-An Yao, Po-Chung Chien, Han-Jung Tsai, Yi-Ru Chen, Jen-Hua Chuang, Pei-Li Chou, Guan-Chiun Lee, Wenwei Lin, Yenshou Lin   +9 more
openaire   +2 more sources

Synthesis of Cytotoxic Benzofurans and Ethers Derivatives of Paeonol

Chemistry & Biodiversity
AbstractPaeonol is a broadly studied natural product due to its many biological activities. Using a methodology previously employed by our research group, 11 derivatives of paeonol were synthesized (seven of them are unpublished compounds), including four ethers and seven benzofurans.
Laura P. R. Figueroa, Helori V. Domingos, Jennifer B. Pardo, Pedro H. O. Santiago, Javier Ellena, Valdemar Lacerda Junior, Letícia V. Costa‐Lotufo, Warley de S. Borges   +7 more
openaire   +2 more sources

Optimization of paeonol-loaded microparticle formulation by response surface methodology

Journal of Microencapsulation, 2015
In this study, a central composite rotatable design based on response surface methodology (RSM) was employed to design and formulate an appropriate paeonol microparticle formulation. Five levels of a three-factor, rotatable, central composite design were used to evaluate the critical formulation variables.
Sha-Sha, Li, Guo-Feng, Li, Li, Liu, Hui, Li, Xiao, Jiang, Xue-Ling, Li, Zhi-Gang, Liu, Ting, Zuo, Li-Dong, Weng, Qiang, Liu   +9 more
openaire   +2 more sources

Paeonol inhibits anaphylactic reaction by regulating histamine and TNF-α

International Immunopharmacology, 2004
Paeonol, a major phenolic component of Moutan Cortex, was known to have antiaggregatory, antioxidant and antiinflammatory activities. In the present study, we tried to elucidate the effects of paeonol on anaphylactic reaction and its mode of action. Paeonol significantly inhibited histamine release from the rat peritoneal mast cells (RPMCs) treated ...
Sung Hoon, Kim, Seung-Ae, Kim, Mi-Kyung, Park, Seung-Hyung, Kim, Young-Doo, Park, Ho-Jeong, Na, Hyung-Min, Kim, Min-Kyu, Shin, Kyoo-Seok, Ahn   +8 more
openaire   +2 more sources

Paeonol

Drugs of the Future, 1996
T. Zhao, J. Liu
openaire   +1 more source

Isolation of Paeonol fromArisaema erubescens

Planta Medica, 1995
S, Ducki, J A, Hadfield, N J, Lawrence, X, Zhang, A T, McGown   +4 more
openaire   +2 more sources

Paeonol

2018
Shi-Ying Yang, Li-Da Du, Yang Lu
openaire   +1 more source

Ueber das Paeonol

Berichte der deutschen chemischen Gesellschaft, 1891
openaire   +1 more source

Ueber das Phenylhydrazon und Ketoxim des Paeonols

Berichte der deutschen chemischen Gesellschaft, 1891
openaire   +1 more source