Results 211 to 220 of about 12,787,233 (297)

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Erratum: The clinical significance of intracranial pressure waveform analysis in brain-injured patients. [PDF]

Crit Care Sci
europepmc   +1 more source

The Peak-End Rule and Retrospective Emotional Valence in Digital Learning Tasks: Evidence from a Word-Learning App. [PDF]

Behav Sci (Basel)
Xie W, Li Z.
europepmc   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Recent major changes to TAIR: updates to the database, website, and Arabidopsis genome. [PDF]

Genetics
Reiser L, Proia A, Bakker E, Subramaniam S, Khosa K, Sawant S, Chen X, Prithvi T, Berardini TZ.   +8 more
europepmc   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Simulating arsenic migration in arid farmland soils under high-arsenic groundwater irrigation in Xinjiang. [PDF]

PLoS One
He J, Deng W, Tuerhong T, Luo Y, Wang M, Song Z, Liu X, Xie X, Zhang Q, Yu E, Sun R.   +10 more
europepmc   +1 more source

A multi-level visual representation dataset for large-scale non-financial information disclosure. [PDF]

Sci Data
Li B, Xia B, Cheng Z, Xu Y, Duan Z.
europepmc   +1 more source

Correction: Performance of several types of beta-binomial models in comparison to standard approaches for meta-analyses with very few studies. [PDF]

BMC Med Res Methodol
Felsch M, Beckmann L, Bender R, Kuss O, Skipka G, Mathes T.   +5 more
europepmc   +1 more source

Calcineurin Inhibitors and Uric Acid Control in Solid Organ Transplantation: A Systematic Review. [PDF]

Med Sci (Basel)
Martino FK, Bogo M, Brunetta L, Fioretti F, Cattarin L, Stefanelli LF, Nalesso F.   +6 more
europepmc   +1 more source