Results 41 to 50 of about 1,114,025 (267)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Improved PageRank Algorithm Based on User Behavior and Page Analysis [PDF]
Jisuanji gongcheng, 2016 In classical PageRank algorithm,transition probability of page is equally distributed to the outlinks.There are few links of new page,so its PR value is generally low.Classical PageRank algorithm is used to calculate the PR value through links,without ...
WANG Xuyang,REN Guosheng
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Halaman Depan Jurnal Sisfokom (Sistem Informasi dan Komputer) Vol. 8 No. 1 2019
Jurnal Sisfokom, 2019 This article contains front-matter of Sisfokom, Volume 8 Number 1 March 2019, which includes a cover page, title page, editorial team, and table of contents.
Editor in Chief Sisfokom
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Halaman Depan Jurnal Sisfokom (Sistem Informasi dan Komputer) Vol. 8 No. 2 2019
Jurnal Sisfokom, 2019 This article contains front-matter of Sisfokom Journal, Volume 8 Number 2 Year 2019, which includes a cover page, title page, editorial team, and table of contents.
Editor in Chief Sisfokom
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The 2-page crossing number of K n
Proceedings of the twenty-eighth annual symposium on Computational geometry, 2012 Around 1958, Hill described how to draw the complete graph $K_n$ with [Z(n) :=1/4\lfloor \frac{n}{2}\rfloor \lfloor \frac{n-1}{2}\rfloor \lfloor \frac{n-2}{2}% \rfloor \lfloor \frac{n-3}{2}\rfloor] crossings, and conjectured that the crossing number $\crg (K_{n})$ of $K_n$ is exactly Z(n).
Bernardo M. Ábrego +4 more
openaire +2 more sources