Results 201 to 210 of about 9,336,586 (256)
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Extramammary Paget's disease: a review of the literature
International Journal of Dermatology, 2018Extramammary Paget's disease (EMPD) is a rare cutaneous malignancy. The disease typically affects older individuals aged 60–80 years and is seen most frequently in postmenopausal Caucasian women and Asian men. EMPD exhibits a predilection for the genital
Robert Simonds, R. Segal, A. Sharma
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Journal of the American Academy of Dermatology, 1986
Summary Extramammary Paget's disease remains a difficult clinical diagnosis and, though biopsy readily establishes the presence of a tumour with an intraepidermal spread, this needs further study so that other tumours with a similar pattern of spread may be excluded. We advocate the use of a panel of readily available peroxidase-labelled antisera to
P P, Anthony, K, Freeman, A P, Warin
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Summary Extramammary Paget's disease remains a difficult clinical diagnosis and, though biopsy readily establishes the presence of a tumour with an intraepidermal spread, this needs further study so that other tumours with a similar pattern of spread may be excluded. We advocate the use of a panel of readily available peroxidase-labelled antisera to
P P, Anthony, K, Freeman, A P, Warin
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Gynecologic Oncology, 2004
Microinvasive squamous cell carcinoma of the vulva is defined as stromal invasion < or =1 mm and is treated by wide local resection. Whether criteria for microinvasive squamous cell carcinoma can be applied to Paget's disease of the vulva is unknown because of the rarity of that disease.We initially evaluated three cases of microinvasive Paget's ...
Thomas, Ewing +3 more
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Microinvasive squamous cell carcinoma of the vulva is defined as stromal invasion < or =1 mm and is treated by wide local resection. Whether criteria for microinvasive squamous cell carcinoma can be applied to Paget's disease of the vulva is unknown because of the rarity of that disease.We initially evaluated three cases of microinvasive Paget's ...
Thomas, Ewing +3 more
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Metabolism, 2018
Juvenile Paget disease (JPD) is a rare disorder, mainly caused by mutations in the gene TNFRSF11B that encodes osteoprotegerin (OPG). Loss of OPG action causes generalized, extremely rapid bone turnover. The clinical manifestations are both skeletal - progressive skeletal deformity that develops in childhood - and extra-skeletal, including hearing loss,
Stergios A. Polyzos +2 more
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Juvenile Paget disease (JPD) is a rare disorder, mainly caused by mutations in the gene TNFRSF11B that encodes osteoprotegerin (OPG). Loss of OPG action causes generalized, extremely rapid bone turnover. The clinical manifestations are both skeletal - progressive skeletal deformity that develops in childhood - and extra-skeletal, including hearing loss,
Stergios A. Polyzos +2 more
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British Journal of Dermatology, 1971
Summary.— A case of perianal Paget's disease is reported and 52 similar cases described in the literature are reviewed. The disease is most commonly associated with an underlying adenocarcinoma of the apocrine glands, but may also be associated with a carcinoma of the rectum.
A, Gunn, H, Fox
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Summary.— A case of perianal Paget's disease is reported and 52 similar cases described in the literature are reviewed. The disease is most commonly associated with an underlying adenocarcinoma of the apocrine glands, but may also be associated with a carcinoma of the rectum.
A, Gunn, H, Fox
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Journal of Endodontics, 2003
A review of the signs, symptoms, and treatment of Paget's disease is presented. Paget, or osteitis deformans, is a chronic, progressive, bone disease of viral etiology. Recent investigations about the causative agent of this disorder have implicated the measles virus of the paramyxovirus family.
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A review of the signs, symptoms, and treatment of Paget's disease is presented. Paget, or osteitis deformans, is a chronic, progressive, bone disease of viral etiology. Recent investigations about the causative agent of this disorder have implicated the measles virus of the paramyxovirus family.
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New England Journal of Medicine, 2017
An 89-year-old man presented with a 1-year history of a nonhealing groin rash that did not respond to antibiotics, antifungal agents, or glucocorticoids. A diagnosis of extramammary Paget’s disease was made by means of a skin biopsy.
Sarah H, Mehrtens, Sriramulu, Tharakaram
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An 89-year-old man presented with a 1-year history of a nonhealing groin rash that did not respond to antibiotics, antifungal agents, or glucocorticoids. A diagnosis of extramammary Paget’s disease was made by means of a skin biopsy.
Sarah H, Mehrtens, Sriramulu, Tharakaram
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Annales de Dermatologie et de Vénéréologie, 2021
Paget's disease (PD) denotes an initially intra-epidermal adenocarcinoma that can later invade the dermis and metastasise. Among the extramammary forms of PD (EMPD), penoscrotal presentations are rarer than the vulvar and perianal forms. Once diagnosis has been confirmed by histopathological examination, a search for associated neoplasia must be ...
J-N, Dauendorffer +7 more
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Paget's disease (PD) denotes an initially intra-epidermal adenocarcinoma that can later invade the dermis and metastasise. Among the extramammary forms of PD (EMPD), penoscrotal presentations are rarer than the vulvar and perianal forms. Once diagnosis has been confirmed by histopathological examination, a search for associated neoplasia must be ...
J-N, Dauendorffer +7 more
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Journal of Cutaneous Medicine and Surgery, 2006
Background: Perianal Pa get's disease is an uncommon intraepithelial neoplasm that involves areas affluent with apocrine glands, most frequently in the female external genitalia, but may also affect the perianal region. Objective: We present the pathologic and clinical management of a case of Paget's disease involving the perianal region, in which ...
Zion, Zibly +4 more
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Background: Perianal Pa get's disease is an uncommon intraepithelial neoplasm that involves areas affluent with apocrine glands, most frequently in the female external genitalia, but may also affect the perianal region. Objective: We present the pathologic and clinical management of a case of Paget's disease involving the perianal region, in which ...
Zion, Zibly +4 more
openaire +2 more sources