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Extramammary Paget disease of the vulva
Seminars in Diagnostic Pathology, 2021Extramammary Paget disease (EMPD) is a rare neoplasm with uncertain histogenesis, usually presenting in the anogenital area, most commonly in the vulva. The disease is characterized by slow grow and high recurrence rates. This article reviews the epidemiological, clinical, morphological, genetic and treatment features of EMPD of the vulva reported in ...
Anastasia M, Konstantinova +1 more
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JAAPA, 2019
ABSTRACT Vulvar Paget disease (VPD) is an unusual and rare adenocarcinoma that can be challenging to diagnose. Although the condition has a high treatment success rate, it can be associated with underlying malignancy, recurrence rates can be high, and patients often need regular and frequent follow-up.
Jennifer, Johnson, Danielle, OʼLaughlin
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ABSTRACT Vulvar Paget disease (VPD) is an unusual and rare adenocarcinoma that can be challenging to diagnose. Although the condition has a high treatment success rate, it can be associated with underlying malignancy, recurrence rates can be high, and patients often need regular and frequent follow-up.
Jennifer, Johnson, Danielle, OʼLaughlin
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Gynecologic Oncology, 1975
Abstract Paget's disease of the vulva and Paget's with an underlying adenocarcinoma may be two separate lesions. The clinical aspects of the two follow entirely different courses. Paget's disease without invasion has a rather indolent behavior and can reoccur locally without subsequent invasion.
W T, Creasman +2 more
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Abstract Paget's disease of the vulva and Paget's with an underlying adenocarcinoma may be two separate lesions. The clinical aspects of the two follow entirely different courses. Paget's disease without invasion has a rather indolent behavior and can reoccur locally without subsequent invasion.
W T, Creasman +2 more
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Acta Obstetricia et Gynecologica Scandinavica, 1996
Paget's disease of the vulva is uncommon and accounts for 1-5% of all vulvar neoplasms (1). Due to its rarity and different disease patterns, we present a clinicopathologic study of five cases seen at our hospital from 1977 to 1995.
C W, Tsai +3 more
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Paget's disease of the vulva is uncommon and accounts for 1-5% of all vulvar neoplasms (1). Due to its rarity and different disease patterns, we present a clinicopathologic study of five cases seen at our hospital from 1977 to 1995.
C W, Tsai +3 more
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Obstetrical & Gynecological Survey, 1990
Thirty-six patients with Paget's disease of the vulva were reviewed. Median age of the patients at diagnosis was 64 years (range 41-84 years). Five patients (14%) had an associated invasive adenocarcinoma of the vulva at the time of diagnosis. Of 31 patients with superficial noninvasive Paget's disease, 28 were available for follow-up.
J P, Curtin +4 more
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Thirty-six patients with Paget's disease of the vulva were reviewed. Median age of the patients at diagnosis was 64 years (range 41-84 years). Five patients (14%) had an associated invasive adenocarcinoma of the vulva at the time of diagnosis. Of 31 patients with superficial noninvasive Paget's disease, 28 were available for follow-up.
J P, Curtin +4 more
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Invasive Paget Disease of the Vulva
International Journal of Gynecological Cancer, 2018Extramammary Paget disease of the vulva (EPDV) is a rare occurrence with an indolent and relapsing course. Progression to invasion occurs in 4% to 19% of cases. The aim of this study is to report clinical-pathological features and outcomes of patients treated for invasive EPDV.Data of consecutive patients treated between 2000 and 2017 for invasive EPDV
Borghi, Chiara +11 more
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Extramammary Paget’s Disease of the Vulva
Journal of Obstetrics and Gynaecology Canada, 2009Extramammary Paget’s disease is a rare neoplastic disorder involving skin bearing apocrine glands . On the vulva it can be intraepithelial or less commonly have an invasive component, and accounts for less than 1% of vulvar neoplasms.1 The more common intraepithelial lesion is classified by the International Society for the Study of Vulvar Disease as a
Clarissa, Bambao, Michael, Shier
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Archives of Dermatology, 1948
THE CLINICAL picture that Paget 1 described in 1874 as a disease of the mammary areola preceding cancer of the mammary gland was soon known to have not only characteristic clinical features but also a peculiar microscopic picture, which entitled it to be classified in a separate group of cutaneous epitheliomatoses.
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THE CLINICAL picture that Paget 1 described in 1874 as a disease of the mammary areola preceding cancer of the mammary gland was soon known to have not only characteristic clinical features but also a peculiar microscopic picture, which entitled it to be classified in a separate group of cutaneous epitheliomatoses.
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Gynecologic Oncology, 2012
Paget’s disease of the vulva is a rare vulvar neoplasm most commonly seen in postmenopausal women. The mean age at diagnosis has been reported to range from 50 to 80 years. Women commonly present with a well-demarcated pink eczematous lesion with white islands of hyperkeratosis, often accompanied by pruritus, vulvar pain, and erythema.
K. Reed +4 more
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Paget’s disease of the vulva is a rare vulvar neoplasm most commonly seen in postmenopausal women. The mean age at diagnosis has been reported to range from 50 to 80 years. Women commonly present with a well-demarcated pink eczematous lesion with white islands of hyperkeratosis, often accompanied by pruritus, vulvar pain, and erythema.
K. Reed +4 more
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Paget's disease of the vulva: A challenge for the gynaecologist
Journal of Gynecology Obstetrics and Human Reproduction, 2021Paget's disease of the vulva is a rare form of extramammary Paget's disease mainly affecting postmenopausal women. Its pathophysiology remains largely unknown. Up to fairly recently, the only treatment for this disease was surgery, often mutilating the vulva, with significant psychosexual repercussions without the assurance of complete therapeutic ...
I, Carton +6 more
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