Results 41 to 50 of about 852 (141)
Practice Patterns in Extramammary Paget's Disease
ABSTRACT Background In patients with Extramammary Paget's Disease (EMPD), a rare intraepithelial adenocarcinoma, wide local excision (WLE) has historically been the standard of treatment despite high rates of positive margins and recurrence. Mohs micrographic surgery (MMS) has demonstrated superior outcomes, yet practice patterns vary due to limited ...
Yasmine Mohseni +4 more
wiley +1 more source
Management of Extramammary Paget's Disease: A Case Report and Review of the Literature
Extramammary Paget's Disease (EMPD) is a rare condition of the skin that often involves the vulva, perianal region, scrotum, penis, and axilla. Although prognosis is generally favorable, it can be associated with neoplasms of the bladder, urethra ...
Rosa Guerra, Subhasis Misra
doaj +1 more source
Chronic macerated plaques over the genitalia in an elderly female: A diagnostic challenge
Extramammary Paget's disease (EMPD) is a rare dermatosis occurring in sites rich in apocrine glands, such as the vulva, anogenital region, and axilla. It can be subdivided into primary and secondary disease.
S Suvarna +4 more
doaj +1 more source
There is no effective treatment for advanced extramammary Paget’s disease (EMPD). The human epidermal growth factor receptor 2 (HER2) protein is often overexpressed in EMPD.
Fumie Hanawa +5 more
doaj +1 more source
ABSTRACT Persistent treatment‐resistant anogenital plaques should not be repeatedly managed as chronic eczema without histopathological confirmation. Early biopsy of atypical or non‐resolving lesions facilitates timely diagnosis of Bowen disease, prevents prolonged diagnostic delay, and enables treatment before progression to invasive squamous cell ...
Shiwani Sharma Acharya +2 more
wiley +1 more source
An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo +14 more
wiley +1 more source
ABSTRACT Pagetoid spread (PS) of anorectal cancer is relatively rare and is associated with poor prognosis compared with Extramammary Paget disease. It is therefore essential to accurately differentiate between the two entities. In PS cases, the primary tumor lesion is usually obvious; however, this is not the case in nonmass‐forming type anorectal ...
Mizunori Yaegashi +3 more
wiley +1 more source
Background Perianal Paget’s disease (pPD) is uncommon, with only about 180 cases documented in the literature. Anorectal carcinoma with pagetoid spread is even rarer.
Taichi Matsubara +10 more
doaj +1 more source
Perianal Paget's Disease: A Case Report
ABSTRACT Perianal Paget's disease is rare and may be secondary to an underlying anorectal adenocarcinoma. Full‐thickness biopsy with immunohistochemistry is key to distinguish primary from secondary disease and to guide staging. Wide local excision is standard, while radiotherapy is a reasonable option when radical surgery is declined.
Daniela Lira +5 more
wiley +1 more source
Extramammary Paget’s disease (EMPD) is a rare neoplasm that usually develops in apocrine gland-bearing areas, such as the vulva, scrotum, and penis. EMPD may present with a focal, multifocal, or an ectopic lesion.
Shoichiro Ishizuki, Yoshiyuki Nakamura
doaj +1 more source

