Rare manifestation of a c.290 C\u3eT, p.Gly97Glu VCP mutation [PDF]
, 2015 Introduction. The valosin-containing protein (VCP) regulates several distinct cellular processes. Consistent with this, VCP mutations manifest variable clinical phenotypes among and within families and are a diagnostic challenge. Methods.
Chou, Tsui-Fen +9 more
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Tumor-Associated Hypercalcemia in a Patient with Paget's Disease
Kaohsiung Journal of Medical Sciences, 2008 Paget's disease of the bone, which is characterized by a focal region of highly exaggerated bone remodeling, is very rare in Asia. Most patients with Paget's disease are asymptomatic; they are normocalcemic and show elevated alkaline phosphatase levels ...
Hao-Chang Hung +4 more
doaj +1 more source
Case of patient with extramammary Paget’s disease
Вестник хирургии имени И.И. Грекова, 2021 Extramammary Paget’s disease is the infrequently diagnosis in surgical practice, representing a diagnostic challenge. The timely verified diagnosis guarantees successful treatment.
A. Z. Tsitskarava +3 more
doaj +1 more source
Medication-related osteonecrosis of the jaw: clinical and practical guidelines [PDF]
, 2016 Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse drug reaction, consisting of progressive bone destruction in the maxillofacial region of patients.
Allen +42 more
core +2 more sources
Meaning behind measurement : self-comparisons affect responses to health related quality of life questionnaires [PDF]
, 2009 Purpose The subjective nature of quality of life is particularly pertinent to the domain of health-related quality of life (HRQOL) research. The extent to which participants’ responses are affected by subjective information and personal reference frames
AJ Carr +28 more
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The role of small RNAs in Paget's associated osteosarcoma [PDF]
, 2018 Small RNAs (sRNAs) are a class of non-coding RNA molecules that arekey regulators of gene expression. SRNAs are also specific biomarkersdue to their dysregulation in disease.
Dalmay, Tamas +2 more
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Severe congestive heart failure in elderly patient with Paget’s disease
Geriatric Care, 2017 Paget’s disease of bone is characterized by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton. Paget’s disease is often asymptomatic, but can be associated with bone pain and other skeletal and non-skeletal ...
Lorenzo Palleschi, Eleonora Nunziata
doaj +1 more source
Intraepidermal malignancy in breast skin: A tale of two tumours
Human Pathology: Case Reports, 2018 Mammary Paget's disease most commonly affects the nipple areolar complex and is frequently associated with an underlying in-situ or invasive breast carcinoma.
Zitong Zhao +5 more
doaj +1 more source
Paget's disease of bone in Tunisia: A study of 69 patients
Indian Journal of Endocrinology and Metabolism, 2020 Context: Paget's disease of bone is a common bone disease with a striking variation in its incidence and characteristics in different parts of the world. It is uncommonly reported in African patients.
Kaouther Maatallah +8 more
doaj +1 more source
VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo. [PDF]
, 2015 Lysosomes are classically viewed as vesicular structures to which cargos are delivered for degradation. Here, we identify a network of dynamic, tubular lysosomes that extends throughout Drosophila muscle, in vivo. Live imaging reveals that autophagosomes
Davis, Graeme W +4 more
core +3 more sources