Results 41 to 50 of about 17,804 (213)

Diagnóstico e tratamento da doença de Paget óssea [PDF]

, 2014
Objective:To conduct a literature review on the diagnosis and management of Paget’s disease of bone. Materials and methods:This scientific statement was generated by a request from the Brazilian Medical Association (AMB) to the Brazilian Society of ...
Bandeira, Francisco, Borba, Victoria Zeghbi Cochenski, Borges, João Lindolfo Cunha, Fontan, Daniele, Fontenele, Thyciara, Griz, Luiz, Lazaretti-Castro, Marise, Maia, Juliana, Mesquita, Patricia   +8 more
core   +3 more sources

Additional file 5: of Effect of a rare genetic variant of TM7SF4 gene on osteoclasts of patients with Pagetâ s disease of bone

, 2017
Gene expression analyses of candidate genes quantified by PCR from cell lysates of in vitro differentiated osteoclasts and normalized by 18S. (PPT 239 kb)
Laurier, Emilie, Amiable, Nathalie, Gagnon, Edith, Brown, Jacques, LaĂŤtitia Michou   +4 more
openaire   +1 more source

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Subtrochanteric Fracture In A Chinese Woman With Paget’s Disease Of Bone And On Long Term Bisphosphonate Therapy: Could It Be An Insufficiency Fracture? [PDF]

Malaysian Orthopaedic Journal, 2011
Paget’s disease is common in Western countries but is very rare in Chinese populations. Although bisphosphonate has been widely used to treat symptomatic Paget’s disease, prolonged use may be associated with insufficiency fracture. We highlight this rare
CK Lee, P Jeremy, S Simmrat, M Azura
doaj  

Protocol for stage 2 of the GaP study (genetic testing acceptability for Paget's disease of bone): A questionnaire study to investigate whether relatives of people with Paget's disease would accept genetic testing and preventive treatment if they were available

BMC Health Services Research, 2008
Background Paget's disease of bone (PDB) disrupts normal bone architecture and causes pain, deformity, deafness, osteoarthritis, and fractures. Genetic factors play a role in PDB and genetic tests are now conducted for research purposes.
McCallum Marilyn, Weinman John, MacLennan Graeme, Marteau Theresa, Entwistle Vikki A, Campbell Marion K, Robertson Clare, Francis Jill, Johnston Marie, Langston Anne L, Miedzybrodska Zosia, Charnock Keith, Ralston Stuart H   +12 more
doaj   +1 more source

Additional file 3: of Effect of a rare genetic variant of TM7SF4 gene on osteoclasts of patients with Pagetâ s disease of bone

, 2017
Gene expression analyses of candidate genes quantified by PCR from cell lysates of in vitro differentiated osteoclasts and normalized by G6PD. (PPT 240 kb)
Laurier, Emilie, Amiable, Nathalie, Gagnon, Edith, Brown, Jacques, LaĂŤtitia Michou   +4 more
openaire   +1 more source

How accurate is your sclerostin measurement?:Comparison between three commercially available sclerostin ELISA kits [PDF]

, 2016
Sclerostin, bone formation antagonist is in the spotlight as a potential biomarker for diseases presenting with associated bone disorders such as chronic kidney disease (CDK-MBD). Accurate measurement of sclerostin is therefore important.
Fisher, Emily, Fraser, William D, Greeves, Julie, Jackson, Sarah, Piec, Isabelle, Tang, Jonathan, Washbourne, Christopher   +6 more
core   +1 more source

Romosozumab and Denosumab Combination Therapy After Denosumab in Postmenopausal Osteoporosis

Arthritis &Rheumatology, Accepted Article.
Background Transition from long‐term denosumab to PTH‐analogs or romosozumab might expose patients to the risk of the so‐called rebound phenomenon. Adding romosozumab to denosumab might represent an option in patients experiencing a fracture while on denosumab.
Giovanni Adami, Francesco Pollastri, Angelo Fassio, Filippo Montanari, Anna Piccinelli, Camilla Benini, Emma Pasetto, Carmen Dartizio, Davide Gatti, Maurizio Rossini, Ombretta Viapiana   +10 more
wiley   +1 more source

Practical consensus recommendatons for Paget's disease in breast cancer

South Asian Journal of Cancer, 2018
Paget's disease of the breast is a rare type of cancer of the nipple–areola complex and that is often associated with an underlying in situ or invasive carcinoma. Diagnosis and treatment of Paget's disease is controversial.
A Gaurav, V Gupta, R Koul, S Dabas, R Sareen, K Geeta, V Arora, Purvish M Parikh, S Aggarwal   +8 more
doaj   +1 more source

Additional file 6: of Effect of a rare genetic variant of TM7SF4 gene on osteoclasts of patients with Pagetâ s disease of bone

, 2017
Raw data of Western Blot analyses. (DOC 30 kb)
Laurier, Emilie, Amiable, Nathalie, Gagnon, Edith, Brown, Jacques, LaĂŤtitia Michou   +4 more
openaire   +1 more source