Mammary-like adenocarcinoma of the vulva associated to Paget's disease: a case report
The Pan African Medical Journal, 2014 Mammary-like adenocarcinoma of the vulva associated to Paget's disease is exceedingly rare. So, it is very important to perform all the pathological and immunohistochemical investigations to achieve differential diagnosis from both a metastatic lesion ...
Sawsen Meddeb +6 more
doaj +1 more source
Long-term randomized trial of intensive versus symptomatic management in Paget's disease of bone: The PRISM-EZ study [PDF]
, 2017 It has been suggested that normalization of bone turnover may improve clinical outcome in Paget’s disease of bone (PDB) by preventing complications such as fractures and the progression of osteoarthritis.
Armamento-Villareal +23 more
core +2 more sources
Molecular Alterations in Osteosarcomas of the Oral and Maxillofacial Region: A Scoping Review
Journal of Oral Pathology &Medicine, EarlyView.ABSTRACT Background Given the rarity and aggressive nature of osteosarcomas (OS) in the oral and maxillofacial region, understanding their molecular alterations is essential to improve diagnosis, prognosis, and guide targeted therapies. This study aimed to map molecular alterations associated with oral and maxillofacial OS, providing an overview of the
Iara Vieira Ferreira +6 more
wiley +1 more source
Clinical features and treatment of perianal Paget’s disease: with report of five cases
结直肠肛门外科Perianal Paget’s disease, also known as perianal eczema-like carcinoma, is a relatively rare malignant disease that can be clinically categorized into primary and secondary perianal Paget’s disease. The disease is highly invasive and clinically difficult
Liu Yaoan +3 more
doaj +1 more source
The incidence Of Paget’s disease of the breast In Benghazi- Libya (During a period of 19 years)
مجلة المختار للعلوم, 2019 Dermatoses of the nipple and areola are rare. The Paget's disease is a common dermatosis, which is presented in the form of a well-demarcated erythematous area, sometimes erosive, oozing or hyperkeratotic.
Tawfik Abuzalout +2 more
doaj +1 more source
p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions. [PDF]
, 2016 The AAA+ ATPase p97/VCP adopts at least three conformations that depend on the binding of ADP and ATP and alter the orientation of the N-terminal protein-protein interaction (PPI) domain into up and down conformations.
Arkin, Michelle +2 more
core
Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction [PDF]
, 2019 p97 is a highly abundant, homohexameric AAA+ ATPase that performs a variety of essential cellular functions. Characterized as a ubiquitin-selective chaperone, p97 recognizes proteins conjugated to K48-linked polyubiquitin chains and promotes their ...
Long, David T. +3 more
core +1 more source
JOR SPINE, Volume 9, Issue 1, March 2026.This study investigated the effect of spinal bone metastasis (BM) on the biomechanical environment of the spine through estimates of load, strength, and the load‐to‐strength ratio (LSR). Our study suggests that task‐specific differences related to cancer, lesion type, and vertebral location differentially affect the biomechanical environment of the ...
Dennis E. Anderson +13 more
wiley +1 more source
Paget’s Disease of the Breast in a Patient with Amyopathic Dermatomyositis
Case Reports in Medicine, 2012 Amyopathic dermatomyositis (AD) can be a part of paraneoplastic syndrome of an underlying malignancy. Paget’s disease is a rare form of breast cancer. We present a very rare case of Paget’s disease associated with AD.
Sirin Yasar +5 more
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Paget’s Breast Disease: A Case Report and Review of the Literature
Frontiers in Surgery, 2017 Paget’s disease of the breast is a rare cancer. This typical clinical case illustrates the different epidemiological, clinical, histological, therapeutic, and evolving aspects of the disease. We report a case of Paget’s disease in a 43-year-old woman who
S. Dubar +8 more
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