Results 11 to 20 of about 11,714 (178)

Fracture of tibial tuberosity in an adult with Paget's disease of the bone – An interesting case and review of literature

Trauma Case Reports, 2021
Introduction: Paget's disease of the bone is a non-malignant skeletal disorder characterized by focal abnormalities in bone remodelling at one or more skeletal sites.
Marjan Raad, Sebastian Ndlovu, Tord Hǿgsand, Saif Ahmed, Mark Norris   +4 more
doaj   +1 more source

Severe congestive heart failure in elderly patient with Paget’s disease

Geriatric Care, 2017
Paget’s disease of bone is characterized by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton. Paget’s disease is often asymptomatic, but can be associated with bone pain and other skeletal and non-skeletal ...
Lorenzo Palleschi, Eleonora Nunziata
doaj   +1 more source

Paget’s Disease Diagnosed on Cranial and Sacroiliac Involvement in Contrast to Normal Alkaline Phosphatase Levels

Türk Osteoporoz Dergisi, 2020
Paget’s disease of bone is characterized by a chronic focal bone remodelling disorder, which is usually detected incidentally during routine imagining examinations.
Gonca Sağlam
doaj   +1 more source

Functional bracing for delayed union of a femur fracture associated with Paget's disease of the bone in an Asian patient: a case report

Journal of Orthopaedic Surgery and Research, 2010
Paget's disease of the bone is a common metabolic bone disease in most European countries, Australia, New Zealand, and North America. Conversely, this disease is rare in Scandinavia, Asia, and Africa.
Fukuta Masashi, Matsumoto Kazu, Ohara Akira, Takigami Iori, Shimizu Katsuji   +4 more
doaj   +1 more source

Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone [PDF]

, 2012
We performed a genetic association study of rare variants and single nucleotide polymorphisms (SNPs) of UCMA/GRP and OPTN genes, in French-Canadian patients with Paget's disease of bone (PDB) and in healthy controls from the same population.
Albagha, Albagha, Avilion, Basu-Roy, Cancela, Chen, Chung, Desmet, Edith Gagnon, Ethel S. Siris, Fahmi, Gabriel Miltenberger-Miltenyi, Goode, Hocking, Jacques P. Brown, Jean Morissette, Laurin, Laurin, Layfield, Laëtitia Michou, Le Jeune, Lefebvre, Lucas, Luu-The, M. Leonor Cancela, Maruyama, Michou, Morissette, Natércia Conceição, Pankiv, Rath, Rezaie, Rousiere, Shankar, Singh, Staden, Surmann-Schmitt, Tagariello, Tong, van Staa, Viegas, Viegas   +41 more
core   +1 more source

Tumor-Associated Hypercalcemia in a Patient with Paget's Disease

Kaohsiung Journal of Medical Sciences, 2008
Paget's disease of the bone, which is characterized by a focal region of highly exaggerated bone remodeling, is very rare in Asia. Most patients with Paget's disease are asymptomatic; they are normocalcemic and show elevated alkaline phosphatase levels ...
Hao-Chang Hung, Horng-Yih Ou, Jehn-Shyun Huang, Ming-Che Chuang, Ta-Jen Wu   +4 more
doaj   +1 more source

Paget's disease of bone in the patient presented with a bowed leg

Clinical Case Reports, 2023
Key Clinical Message In dealing with bowed limbs along with increased alkaline phosphatase (ALP), even if the typical changes to the face are not very noticeable at first glance, Paget's disease of the bone (PDB) should be suspected, and the necessary ...
Mehrzad Hajialiloo, Sepideh Tahsini Tekantapeh   +1 more
doaj   +1 more source

Paget’s disease of bone: A rare case in a patient under 40 years of age

Human Pathology Reports, 2021
Paget’s disease of bone is a rare diagnosis in patients under 40 years of age. We report a case diagnosed in a 35-year-old patient with suspected symptomatic presentation at the age of 30 years during pregnancy.
Erina Melva McKinney, Anders R. Meyer, Elizabeth J. Friedman, Brian MacNeille Everist, Candice E. Rose   +4 more
doaj   +1 more source

Optineurin functions for optimal immunity [PDF]

, 2018
Optineurin (OPTN) was identified 20 years ago in a yeast-two-hybrid screen with a viral protein known to inhibit the cytolytic effects of tumor necrosis factor.
Slowicka, Karolina, van Loo, Geert
core   +1 more source

Five-year follow-up of Japanese patients with Paget's disease of the bone after treatment with low-dose oral alendronate: a case series

Journal of Medical Case Reports, 2010
Introduction Paget's disease of the bone is characterized by focal abnormalities of increased bone turnover affecting one or more sites throughout the skeleton.
Wada Takuro, Takada Junichi, Iba Kousuke, Yamashita Toshihiko   +3 more
doaj   +1 more source