Rare manifestation of a c.290 C\u3eT, p.Gly97Glu VCP mutation [PDF]
, 2015 Introduction. The valosin-containing protein (VCP) regulates several distinct cellular processes. Consistent with this, VCP mutations manifest variable clinical phenotypes among and within families and are a diagnostic challenge. Methods.
Chou, Tsui-Fen +9 more
core +4 more sources
Medication-related osteonecrosis of the jaw: clinical and practical guidelines [PDF]
, 2016 Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse drug reaction, consisting of progressive bone destruction in the maxillofacial region of patients.
Allen +42 more
core +2 more sources
PAGET’S DISEASE OF THE BONE: AN UNUSUAL CAUSE OF LOW BACK PAIN IN AN ADULT MALE [PDF]
Romanian Journal of Rheumatology, 2016 Paget’s disease of the bone (PDB) or osteitis deformans is a chronic metabolic bone disorder, characterized by focal increase in bone resorption, followed by a rapid and abnormal bone repair with a disorganized and excessive bone formation, leading to ...
Iulian Resmerita +2 more
doaj +1 more source
The role of small RNAs in Paget's associated osteosarcoma [PDF]
, 2018 Small RNAs (sRNAs) are a class of non-coding RNA molecules that arekey regulators of gene expression. SRNAs are also specific biomarkersdue to their dysregulation in disease.
Dalmay, Tamas +2 more
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Meaning behind measurement : self-comparisons affect responses to health related quality of life questionnaires [PDF]
, 2009 Purpose The subjective nature of quality of life is particularly pertinent to the domain of health-related quality of life (HRQOL) research. The extent to which participants’ responses are affected by subjective information and personal reference frames
AJ Carr +28 more
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A Case of Paget’s Disease with Scapula Involvement
Türk Osteoporoz Dergisi, 2015 Paget’s disease is a common bone disorder which is characterized by excessive bone turnover. This condition rarely involves sternum, patella, scapula, hand, foot and facial bones. A 65-year-old male patient was admitted to our outpatient clinic with the
Nilgün Mesci +3 more
doaj +1 more source
Diagnóstico e tratamento da doença de Paget óssea [PDF]
, 2014 Objective:To conduct a literature review on the diagnosis and management of Paget’s disease of bone. Materials and methods:This scientific statement was generated by a request from the Brazilian Medical Association (AMB) to the Brazilian Society of ...
Bandeira, Francisco +8 more
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Paget’s Disease of Maxilla with Paranasal Sinuses: A Case Report [PDF]
Journal of Clinical and Diagnostic ResearchPaget’s disease of bone is a chronic skeletal disorder affecting predominantly elderly individuals. The pelvic girdle is the most common site to be affected; however, other sites such as long bones, spine, and skull are also frequently affected.
Amurtham Veeramani +4 more
doaj +1 more source
Acquired Chiari Type 1 Malformation Secondary to Paget’s Disease of the Bone: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2021 Chiari type 1 malformations are characterised by caudal descent of cerebellar tonsil into foramen magnum. Usually it is congenital. Paget’s disease causing acquired chiari type 1 malformation is rare with only five reported cases in the literature.
Srestha Khan +3 more
doaj +1 more source
VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo. [PDF]
, 2015 Lysosomes are classically viewed as vesicular structures to which cargos are delivered for degradation. Here, we identify a network of dynamic, tubular lysosomes that extends throughout Drosophila muscle, in vivo. Live imaging reveals that autophagosomes
Davis, Graeme W +4 more
core +3 more sources