Results 41 to 50 of about 11,488 (177)
Introduction Paget’s disease of bone is usually asymptomatic in most cases. The neurosurgeon should be familiar with the common presentation and complications.
Ahmed Hamdy Ashry +3 more
doaj +1 more source
Paget’s disease of the bone (early diagnosis): How far is far away? [PDF]
Introduction. Paget’s disease of the bone is a skeleton condition affecting bone remodelling of unknown cause. Bone formation and resorption, as parts of bone turnover which are normally coupled in healthy skeleton, in this condition are disconnected. We
Adina Ghemigian +7 more
doaj +1 more source
Use of Zoledronic Acid in the Treatment of Paget's Disease [PDF]
This review examines the use of zoledronic acid in the treatment of Paget’s disease of bone. It begins with a brief discussion of the theories of pathogenesis of Paget’s disease, its clinical manifestations, and the history of bisphosphonate treatment in
Krane, Stephen Martin +1 more
core
Implicit self-comparisons against others could bias quality of life assessments [PDF]
Objectives: To explore how patient-reported health related quality of life (HRQL) and global health status are affected by use of differing personal reference frames.
Fayers, Peter +2 more
core +1 more source
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang +10 more
wiley +1 more source
Cranial Paget’s Disease: A Case Report [PDF]
Scientific BACKGROUND: Paget’s disease is mostly asymptomatic. Neurological syndromes are uncommon but include headache, dementia, brain stem and cerebellar dysfunction, cranial neuropathies, myelopathy, cauda equina syndrome and radiculopathies.
Fazilet Hız +5 more
doaj
Romosozumab and Denosumab Combination Therapy After Denosumab in Postmenopausal Osteoporosis
Background Transition from long‐term denosumab to PTH‐analogs or romosozumab might expose patients to the risk of the so‐called rebound phenomenon. Adding romosozumab to denosumab might represent an option in patients experiencing a fracture while on denosumab.
Giovanni Adami +10 more
wiley +1 more source
An Investigation of Hyperostosis Frontalis Interna in a Modern Anatomical Body Donor Population
ABSTRACT This research sought to examine the prevalence and severity of hyperostosis frontalis interna (HFI) in the Chicagoland anatomical body donor population. The study further aimed to elucidate potential demographic risk factors for HFI, including sex, age at death, and structural vulnerability index (SVI), as well as any common comorbidities, as ...
Amy C. Beresheim, Amanda Hall
wiley +1 more source
Paget’s disease of bone is the most common metabolic bone disease after osteoporosis and affects 2-4% of adults over 55 years of age. Its etiology is only partly understood and includes both genetic and environmental factors.
I. Bertoldi +3 more
doaj +1 more source
Long-term randomized trial of intensive versus symptomatic management in Paget's disease of bone: The PRISM-EZ study [PDF]
It has been suggested that normalization of bone turnover may improve clinical outcome in Paget’s disease of bone (PDB) by preventing complications such as fractures and the progression of osteoarthritis.
Armamento-Villareal +23 more
core +2 more sources

