Results 61 to 70 of about 11,488 (177)

Alterations of bone proteins in medication‐related osteonecrosis of the jaw

European Journal of Oral Sciences, Volume 133, Issue 2, April 2025.
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert, Phillipp Brockmeyer, Philipp Kauffmann, Jan Wiegel, Florian Lautenbacher, Nicolai Miosge, Boris Schminke   +6 more
wiley   +1 more source

Molecular Alterations in Osteosarcomas of the Oral and Maxillofacial Region: A Scoping Review

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Given the rarity and aggressive nature of osteosarcomas (OS) in the oral and maxillofacial region, understanding their molecular alterations is essential to improve diagnosis, prognosis, and guide targeted therapies. This study aimed to map molecular alterations associated with oral and maxillofacial OS, providing an overview of the
Iara Vieira Ferreira, Reydson Alcides de Lima‐Souza, Moisés Willian Aparecido Gonçalves, Carlos Takahiro Chone, Arthur Antolini‐Tavares, Albina Altemani, Fernanda Viviane Mariano   +6 more
wiley   +1 more source

Determinants of quality of life in Paget's disease of bone

Revista Brasileira de Reumatologia
Objective: To evaluate the parameters associated with quality of life in patients with Paget's disease of bone. Methods: Patients with Paget's disease of bone were evaluated with SF-36 and WHOQOL-bref questionnaires.
Gláucio Ricardo Werner de Castro, Silvania Ana Fernandes de Castro, Ivanio Alves Pereira, Adriana Fontes Zimmermann, Maria Amazile Toscano, Fabricio Souza Neves, Maria Aparecida Scottini, Juliane Paupitz, Julia Salvan da Rosa, Ziliani Buss, Tânia Silvia Fröde   +10 more
doaj   +1 more source

Atypical presentation of Paget's disease with secondary osteomyelitis of mandible

Journal of Indian Academy of Oral Medicine and Radiology, 2017
Paget's disease (PD) is a chronic progressive disease of the bone characterized by abnormal bone resorption and deposition affecting either single bone (monostotic) or many bones (polyostotic).
Sadaksharam Jayachandran, Ramiah Vasudevi, Luis Kayal   +2 more
doaj   +1 more source

LC–MS/MS application for urine free pyridinoline and free deoxypyridinoline: Urine markers of collagen and bone degradation [PDF]

, 2016
Background: Pyridinium cross-links Pyridinoline (PYD) and Deoxypyridinoline (DPD) are established markers of collagen degradation. Measurement of PYD and DPD can be used to evaluate changes in bone turnover in patients with metabolic bone disease and to ...
Behrens, Black, Coleman, Delmas, Delmas, Eyre, Fassbender, Fujikawa, Fujimoto, Garnero, Gineyts, Giunta, Hart, Hou, Imada, Kadavil, Kindt, Knott, Krabben, Kraenzlin, Meddah, Monticelli, Müller, Nagasaka, Nur, Roth, Shaw, Soylu, Sroga, Steinmann, Stone, Tanimoto, Tuck, Uebelhart, Vesper, Westgard, Yeowell   +36 more
core   +1 more source

Metastatic Spine Disease Alters Vertebral Load‐To‐Strength Ratios in Cancer Patients Compared to Healthy Individuals

JOR SPINE, Volume 9, Issue 1, March 2026.
This study investigated the effect of spinal bone metastasis (BM) on the biomechanical environment of the spine through estimates of load, strength, and the load‐to‐strength ratio (LSR). Our study suggests that task‐specific differences related to cancer, lesion type, and vertebral location differentially affect the biomechanical environment of the ...
Dennis E. Anderson, Mario Keko, Joanna James, Brett T. Allaire, David Kozono, Patrick F. Doyle, Heejoo Kang, Sarah Caplan, Tracy Balboni, Alexander Spektor, Mai Anh Huynh, Mary L. Bouxsein, David B. Hackney, Ron N. Alkalay   +13 more
wiley   +1 more source

Difficulties in diagnosis and treatment of Paget’s disease

Family Medicine & Primary Care Review, 2016
Paget’s disease is a rare finding in Poland. It is a disorder of the osteoarticular system, which, in adults, mostly affects people over 55 years of age.
Aleksandra Kawalec, Aleksandra Zdrojowy-Wełna, Grażyna Bednarek-Tupikowska   +2 more
doaj   +1 more source

Paget's disease of bone-associated osteosarcoma: molecular basis, signs and symptoms, treatment and research [PDF]

, 2015
Darrell Green is a Big C-funded molecular biologist at the University of East Anglia, performing research towards a PhD. He works with Professor Tamas Dalmay, Head of Biological Sciences and Chair of RNA Biology at the University of East Anglia and ...
Dalmay, Tamas, Fraser, William, Green, Darrell   +2 more
core  

Fanconi Syndrome After a Single Exposure to Intravenous Zoledronic Acid

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Bisphosphonates are commonly used to reduce fracture risk in patients with osteoporosis, in those with malignant metastatic bone disease and for treatment of malignant hypercalcaemia. We present the case of a woman in her 80s admitted with recurrent falls who developed Fanconi syndrome after a single dose of intravenous Zoledronic acid despite
Rita Deb, Muhammad Elboghdady, Alvin Shrestha   +2 more
wiley   +1 more source

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source