Results 71 to 80 of about 11,488 (177)

PAGET'S DISEASE: CURRENT TREATMENT MODALITIES

Современная ревматология, 2010
Paget's disease is a chronic local bone disease included into a group of metabolic osteopathies in which rearrangement foci emerge in one or several bones.
Yulia Leonidovna Korsakova
doaj   +1 more source

Proteomic Signatures Over Age Reveal Significant Changes From Infancy Till Late Adulthood

Advanced Biology, Volume 10, Issue 1, January 2026.
Age‐specific changes in the serum proteome were investigated across the entire lifespan, from infancy till late adulthood by analyzing 178 proteins in serum samples of healthy individuals. Using various analyses approaches, distinct protein expression profiles and four protein patterns during aging were identified.
Eveline M. Delemarre, Hidde M. Smits, Debbie van Baarle, Marlies A. van Houten, Fiona R. M. van der Klis, Helen L. Leavis, Joel A. G. van Roon, Lilly M. Verhagen, Joanne G. Wildenbeest, Femke van Wijk, Julia Drylewicz, Stefan Nierkens   +11 more
wiley   +1 more source

A woman with raised alkaline phosphatase and forearm deformity [PDF]

, 2011
published_or_final_versio
Chow, WS, Kung, AWC, Lam, JKY, Lam, KSL, Tan, KCB, Tso, AWK   +5 more
core   +1 more source

Management of Cervical Root Resorption on the Palatal Aspect Using Combined Internal and External Surgical Approaches: A Case Report Study

Case Reports in Dentistry, Volume 2026, Issue 1, 2026.
External cervical resorption (ECR) is a progressive disease that occurs at the cervical region of the tooth, developing beneath the epithelial attachment. ECR is often asymptomatic and detected in routine radiographic examinations. This condition can significantly impact the long‐term survival of the affected tooth.
Sahar Shafagh, Marjan Bolbolian, Mahsa Zohdi, Kevin Seymour   +3 more
wiley   +1 more source

Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction [PDF]

, 2019
p97 is a highly abundant, homohexameric AAA+ ATPase that performs a variety of essential cellular functions. Characterized as a ubiquitin-selective chaperone, p97 recognizes proteins conjugated to K48-linked polyubiquitin chains and promotes their ...
Long, David T., Rycenga, Halley B., Wolfe, Kelly B., Yeh, Elizabeth S.   +3 more
core   +1 more source

Evaluation of Cell‐Extracellular Vesicle Interaction Using a Microfluidic Microsystem (CellExoChip)

Advanced Materials Technologies, Volume 10, Issue 23, December 3, 2025.
A new microfluidic platform, the CellExoChip, reveals how cancer cells interact with exosomes to influence metastasis. This device isolates cancer cells and tracks their uptake exosomes and secretion of their exosomes in response to other exosomes. Lung cancer cells are showed preferentially absorb and respond to their own exosomes—hinting at a hidden ...
Nna‐Emeka Onukwugha, Zeqi Niu, Abha Kumari, Scott Smith, Grace Li, Kruthi Srinivasa Raju, Joseph Marvar, Thomas Leekley, Shawn Fortna, Yoon‐Tae Kang, Sunitha Nagrath   +10 more
wiley   +1 more source

Prophylactic zoledronic acid therapy to prevent or modify Paget’s disease of bone progression in adults with SQSTM1 mutations: the ZiPP RCT

Efficacy and Mechanism Evaluation
Background Paget’s disease of bone is characterised by focal abnormalities of bone turnover resulting in various complications. It often presents at an advanced stage with irreversible bone damage. At this point, the symptomatic benefits of treatment are
Jonathan Phillips, Deepak Subedi, Steff C Lewis, Catriona Keerie, Stuart H Ralston   +4 more
doaj   +1 more source

Genetic aspects of Paget’s disease of bone [PDF]

, 2004
Paget’s disease of bone (PDB) is a metabolic bone disease characterized by excessive bone resorption and formation due to increased osteoclasts activity.
Brandi, Maria Luisa, Falchetti, Alberto, Marini, Francesca, Masi, Laura   +3 more
core  

Florid cemento-osseous dysplasia: report of a case documented with clinical,radiographic, biochemical and histological findings [PDF]

, 2013
Florid cemento-osseous dysplasia (FCOD) has been described as a condition that characteristically affects the jaws of middle-aged black women. This condition has also been classified as gigantiform cementoma, chronic sclerosing osteomyelitis, sclerosing ...
Baris, Emre, Bozkaya, Süleyman, Ergün, Gülfem, Kutluay Köklü, Harika, Çankal, Dilek Aynur   +4 more
core   +1 more source

Further Evidence That Chondrocalcinosis 1 (CCAL1) is a Confirmed Mendelian Phenotype With a Known Molecular Basis

American Journal of Medical Genetics Part A, Volume 197, Issue 12, December 2025.
ABSTRACT Chondrocalcinosis (CCAL), also known as calcium pyrophosphate dihydrate deposition disease (CPPDD), is a frequent multifactorial condition in the elderly, but there are two rare autosomal dominant Mendelian forms, CCAL1 (OMIM %600668) and CCAL2. Only three families with molecularly proven CCAL1 have been reported.
Anna‐Christina Pansa, Mareike Selig, Markus Wingendorf, Matthew A. Brown, Oliver Bartsch   +4 more
wiley   +1 more source