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Extramammary Paget Disease: A Review of the Literature-Part I: History, Epidemiology, Pathogenesis, Presentation, Histopathology, and Diagnostic Work-up.

Dermatologic Surgery, 2019
BACKGROUND Extramammary Paget disease (EMPD) is a rare malignancy with unclear pathophysiology that occurs predominantly on apocrine rich skin. Surgery is the treatment of choice; however, procedures tend to be extensive and associated with a high rate ...
C. Morris, E. Hurst
semanticscholar   +1 more source

Extramammary Paget's disease

Clinics in Dermatology, 1993
E xtramammary Paget’s disease (EMPD) is an epithelial disorder usually observed in cutaneous apocrine gland-bearing regions. This condition may be associated with either subjacent or distant malignancies or may potentially be an invasive adenocarcinoma sui gene+. Clinically it is usually recognized as a nonhealing eczematous lesion.
openaire   +2 more sources

Extramammary Paget’s Disease

Nishi Nihon Hifuka, 1979
外陰部ページェット病の7例について, 電顕的, 酵素組織化学的検索をおこない, 表皮のページェット細胞と下床の腺癌の関係, ページェット細胞の本態と由来について考察した。表皮のページェット細胞と下床の腺癌の分化度の差については, 表皮内においてページェット細胞の分化にたいし何らかの抑制が働いている可能性が示唆された。下床の腺癌はあきらかにアポクリン腺癌であり, 表皮のページェット細胞も分化度は低いが, 自験例はすべてアポクリン腺への分化を示していると考えられた。
Masayuki NISHIMURA   +3 more
openaire   +1 more source

Single‐agent taxane is useful in palliative chemotherapy for advanced extramammary Paget disease: a case series

British Journal of Dermatology, 2019
Extramammary Paget's disease (EMPD) is a rare cutaneous malignancy that mainly affects the genital area in the older population. In most EMPD cases, tumour cells are localised to the epidermis, and prognosis is relatively favourable. However, once tumour
M. Kato   +6 more
semanticscholar   +1 more source

Extramammary Paget’s Disease

2018
Extramammary Paget’s disease (EMPD) is a rare, slow-growing intraepithelial adenocarcinoma typically localized to areas of apocrine gland distribution outside the mammary glands. EMPD typically involves the vulva, perianal area, and male genitalia, with rare sites including the thighs, buttocks, axilla, eyelids, and external ear canal.
Nathalie C. Zeitouni, Jose A. Cervantes
openaire   +1 more source

Extramammary Paget's disease.

Southern medical journal, 2000
Extramammary Paget's disease (EMPD) is an uncommon but distinctive tumor. The lesion is defined as an intra-epidermal neoplasm. The lesion may be accompanied by an invasive adenocarcinoma or in situ adenocarcinoma of apocrine glands. Visceral carcinoma may also coexist or develop.
N J, Mehta, R, Torno, T, Sorra
openaire   +3 more sources

KS-EMPD-1: a novel cell line of primary extramammary Paget’s disease

Human Cell, 2023
Takamichi Ito   +4 more
semanticscholar   +1 more source

Therapeutic Outcomes and Survival Analysis of Extramammary Paget's Disease: A multicentre retrospective study of 249 patients.

Journal of American Academy of Dermatology, 2023
H. Escolà   +30 more
semanticscholar   +1 more source

Extramammary Paget’s Disease

2014
Extramammary Paget’s disease, originally described by Crocker in 1889, is a rare apocrine adenocarcinoma that appears in the epidermis and from there may extend into the epithelial structures of adnexa and dermis. The pathogenesis of EMPD is still controversial. There are two different forms of EMPD with distinct pathogenetic mechanisms.
Irina Margaritescu, A. Doru Chirita
openaire   +1 more source

Extramammary paget disease of the penoscrotal region.

Pathology, Research and Practice, 2022
P. Patwardhan, G. Quiroga-Garza
semanticscholar   +1 more source

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