Results 31 to 40 of about 4,852,169 (202)
A 59-year-old man presented with a well-demarcated, tender ulcer at the base of the penile shaft that had been present for approximately five years. The ulcer had been responsive neither to topical antibacterials, antifungals, and glucocorticoids nor to oral acyclovir.
Anolik, Robert +5 more
openaire +4 more sources
We report the case of a 60-year-old man with penile-scrotal extramammary Paget disease (EMPD). The patient initially underwent Mohs micrographic surgery, but the margins remained positive after several sections; multiple scouting punch biopsies used to define the extent of the tumor were also positive.
Hartman, Rachael +4 more
openaire +4 more sources
Androgen receptor and 5α-reductase immunohistochemical profiles in extramammary Paget disease [PDF]
Background Extramammary Paget disease is an uncommon skin tumour occurring mostly in the genitoperineal region. Previous reports have shown frequent expression of androgen receptor, suggesting a tumour-proliferative effect of androgens on Paget cells ...
45941 +14 more
core +1 more source
Paget's disease most commonly affects the breast. Extramammary involvement is rare, and the most commonly affected sites are the vulva, anus, perianal region, and axilla. The disease may progress to invasive adenocarcinoma or synchronous cancers.
Ornella Sari Cassol +5 more
doaj +1 more source
EMPD is a rare condition that poses difficulties of diagnosis and management. Suspicious skin lesions not responding to topical therapy after four to six weeks should be biopsied to exclude EMPD. There is an associated malignancy in 20% to 30% of cases and a detailed investigation of the patient should be carried out at presentation to exclude invasive
Crosbie, Emma; id_orcid 0000-0003-0284-8630 +3 more
openaire +4 more sources
Depigmentation of the vulvar area: Is it an alarming sign?
A 34‐year‐old female patient presented with recurrent bilateral hypopigmented macules on the labia majora. The lesions were treated with topical steroids, which led to mild improvement, but erosive plaques developed after discontinuing the treatment ...
Reem Diab +5 more
doaj +1 more source
Evidence-Based Clinical Practice Guidelines for Extramammary Paget Disease
Importance: Extramammary Paget disease (EMPD) is a frequently recurring malignant neoplasm with metastatic potential that presents in older adults on the genital, perianal, and axillary skin.
Zhou, Youwen +51 more
core +4 more sources
Extramammary Paget Disease of the Vulva - Case Report [PDF]
Extramammary Paget disease (EPD) is a rare malign neoplasm that may affect the vulva and has manifestations common to benign diseases such as itching, pain and eczema. This leads to delay in diagnosis and consequent worse prognosis.
Bianca Ruschel Hillmann +2 more
doaj +2 more sources
Case reports- extramammary Paget's disease [PDF]
Two patients with extramammary Paget′s disease are being reported. The first case was a 60-year-old male who presented with gradually progressive pruritic ulcerated lesion over perianal region not responding to various topical medications ...
Santanu Banerjee +2 more
core +1 more source
Extramammary Paget's disease of the Vulva [PDF]
Vulvar Paget's disease is an extremely rare neoplasm that accounts for less than 1% of the vulvar malignancies. We present a case of a 75-year-old woman, who had an eczematoid lesion involving the labia majora and minora bilaterally, with infiltration to the clitoris. Enlarged non-fixed lymph nodes were palpable in the inguinal region bilaterally.
Paschalis, Gavriilidis +2 more
openaire +2 more sources

