Results 81 to 90 of about 10,354,029 (272)

p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions. [PDF]

, 2016
The AAA+ ATPase p97/VCP adopts at least three conformations that depend on the binding of ADP and ATP and alter the orientation of the N-terminal protein-protein interaction (PPI) domain into up and down conformations.
Arkin, Michelle, Bulfer, Stacie, Chou, Tsui-Fen   +2 more
core  

Perianal Paget's disease [PDF]

Postgraduate Medical Journal, 1977
Summary Paget's disease involves the ducts of apocrine glands and the overlying epidermis and is considered to be locally neoplastic. It is capable of developing into invasive carcinoma and in this event the prognosis is poor. The perianal skin may be affected by Paget's disease.
M R, Lock, D R, Katz, A, Parks, J P, Thomson   +3 more
openaire   +2 more sources

Alterations of bone proteins in medication‐related osteonecrosis of the jaw

European Journal of Oral Sciences, Volume 133, Issue 2, April 2025.
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert, Phillipp Brockmeyer, Philipp Kauffmann, Jan Wiegel, Florian Lautenbacher, Nicolai Miosge, Boris Schminke   +6 more
wiley   +1 more source

A Case of Chronic and Relapsing Paget Disease of the Vulva [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Extramammary Paget disease is a rare neoplastic condition that more commonly affects postmenopausal Caucasian women. Although the vulvar area is the most frequently affected location, it corresponds solely to 1 to 2% of all vulvar malignancies. A 72-year-
Rita Bouceiro-Mendes, Maria Mendonça-Sanches, Luís Soares-de-Almeida, Isabel Correia-Fonseca   +3 more
doaj   +2 more sources

Prevalence of Hypercementosis in Radiographic Studies: A Systematic Review and Meta‐Analysis With Clinical Implications for Endodontic Assessment

International Endodontic Journal, EarlyView.
ABSTRACT Background Hypercementosis is a non‐neoplastic condition characterized by excessive cementum deposition along the root surface, resulting in altered apical morphology. Although often asymptomatic and detected incidentally on radiographs, changes in apical contour may influence anatomical complexity in endodontic treatment.
Carlos Segura‐Raya, Víctor Diaz‐Flores, Milagros Martín‐Jiménez, Juan J. Segura‐Egea   +3 more
wiley   +1 more source

Molecular Alterations in Osteosarcomas of the Oral and Maxillofacial Region: A Scoping Review

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Given the rarity and aggressive nature of osteosarcomas (OS) in the oral and maxillofacial region, understanding their molecular alterations is essential to improve diagnosis, prognosis, and guide targeted therapies. This study aimed to map molecular alterations associated with oral and maxillofacial OS, providing an overview of the
Iara Vieira Ferreira, Reydson Alcides de Lima‐Souza, Moisés Willian Aparecido Gonçalves, Carlos Takahiro Chone, Arthur Antolini‐Tavares, Albina Altemani, Fernanda Viviane Mariano   +6 more
wiley   +1 more source

Vulvo-Perineal and Perianal Paget Disease. Radical Excision and Reconstruction with Singapore Flap

Acta Medica, 2019
Extramammary Paget disease (EMPD) is an uncommon intraepithelial malignancy, affecting the vulvo-perineal and perianal region, occurring in 6.5% of all Paget diseases.
Theodoros Panoskaltsis, Theofanis Panagiotis Arkoumanis, Nikolaos Panagopoulos, Dimitrios Mastorakos   +3 more
doaj   +1 more source

Isolation of Acanthamoeba isolates belonging to T2, T3, T4 and T7 genotypes from environmental samples in Ankara, Turkey [PDF]

, 2004
Acanthamoeba keratitis is a blinding infection that is becoming increasingly important in human health. Early diagnosis is a prerequisite for successful treatment and requires identification of Acanthamoeba at the genotypic level.
Jayasekera, S., Khan, Naveed Ahmed, Kiliç, A., Sissons, J., Tanyuksel, M.   +4 more
core  

Interventions for the treatment of Paget's disease of the vulva.

Cochrane Database of Systematic Reviews, 2019
BACKGROUND This is an updated version of the original Cochrane Review published in Issue 10, 2013.Extramammary Paget's disease is a rare form of superficial skin cancer. The most common site of involvement is the vulva.
K. Edey, E. Allan, J. Murdoch, S. Cooper, A. Bryant   +4 more
semanticscholar   +1 more source

Autogenous Demineralized Dentin Graft–Based Strategies With or Without I‐PRF and Metronidazole for Ridge Preservation in Infected Sockets: A Randomized Clinical Trial

Journal of Periodontal Research, EarlyView.
This randomized controlled trial evaluated the efficacy of demineralized dentin graft (DDG) combined with injectable platelet‐rich fibrin (I‐PRF) and metronidazole (MTZ) versus DDG with or without I‐PRF in alveolar ridge preservation (ARP) of infected extraction sockets.
Mohamed Talaat Elbehwashy, Manal Mohamed Hosny, Ahmed Elfana, Heba Ahmed Saleh, Karim Fawzy El‐Sayed   +4 more
wiley   +1 more source