Results 171 to 180 of about 79,528 (266)

Clinical Features of Cellular Senescence Pathways in Severe Asthma

Allergy, EarlyView.
In bronchial biopsies, SASP and p53 pathway enrichment scores are elevated in severe asthma versus non‐severe asthma and healthy controls. SASP enrichment is validated in the independent NOVA cohort. SASP enrichment is also elevated in nasal brushings of participants with nasal polyps, independently of asthma status.
Woo‐Jung Song, Nazanin Zounemat Kermani, Ali Versi, Stephany Sánchez‐Ovando, Jodie Louise Simpson, Peter A. Wark, Katherine Joanne Baines, Sven‐Erik Dahlén, Ratko Djukanovic, Yike Guo, Ian M. Adcock, Kian Fan Chung, on behalf of the U‐BIOPRED Study Group, Mahmoud. I. Abdel‐Aziz, Ian M. Adcock, Lars I. Andersson, Charles Auffray, Yusef E. Badi, Per Bakke, Aruna T. Bansal, Frederic Baribaud, Stewart A. Bates, Elisabeth H. Bel, Jeanette Bigler, Bo Billing, Hans Bisgaard, Michael J. Boedigheimer, Klaus Bønnelykke, Joost Brandsma, Paul Brinkman, Enrica Bucchioni, Dominic Burg, Andrew Bush, Massimo Caruso, Romanas Chaleckis, Pascal Chanez, Kian Fan Chung, T. Checa, Chris H. Compton, Julie Corfield, Danen Cunoosamy, Arnaldo D'Amico, Barbro Dahlén, Sven‐Erik Dahlén, Bertrand De Meulder, Ratko Djukanovic, Veit J. Erpenbeck, Damijan Erzen, K. Fichtner, Louise J. Fleming, Elena Formaggio, Stephen J. Fowler, Urs Frey, Martina Gahlemann, Thomas Geiser, Victoria Goss, Yike Guo, Simone Hashimoto, John Haughney, Gunilla Hedlin, Pieter‐Paul W. Hekking, Timothy Higenbottam, Jens M. Hohlfeld, Cecile Holweg, Ildiko Horvath, Peter Howarth, Anna J. James, Richard G. Knowles, Johan Kolmert, Jon Konradsen, Norbert Krug, Nikos Lazarinis, C.‐X. Li, Matthew J. Loza, Rene Lutter, Alexander Manta, Sarah Masefield, Anke H. Maitland‐van der Zee, John G. Matthews, Alexander Mazein, Roelinde J. M. Middelveld, Montserrat Miralpeix, Paolo Montuschi, Jacek Musial, Sharon Mumby, David Myles, Björn Nordlund, Ioannis Pandis, Stelios Pavlidis, Anthony Postle, P. Powel, G. Praticò, M. Puig Valls, N. Rao, Stacey Reinke, John Riley, Amanda Roberts, Graham Roberts, Anthony Rowe, Thomas Sandström, Jim P. R. Schofield, Wolfgang Seibold, Dominic E. Shaw, R. Sigmund, Florian Singer, Paul J. Skipp, M. Smicker, Ana R. Sousa, Maria Sparreman‐Mikus, Peter J. Sterk, Marika Ström, Kai Sun, Bob Thornton, Mohib Uddin, Ali Versi, Jorgen Vestbo, Nadja H. Vissing, Scott S. Wagers, Åsa Wheelock, Craig E. Wheelock, Susan J. Wilson, Valentyna Yasinska, Nazanin Zounemat Kermani   +122 more
wiley   +1 more source

Spatiotemporal characterization of placental hypoxia and microvascular dysfunction in a preeclampsia rat model using photoacoustic and contrast-enhanced ultrasound. [PDF]

Quant Imaging Med Surg
Zhang B, Pang H, Yang H, Luo H.
europepmc   +1 more source

Mapping Palaeolithic Imprints: Spatial Analysis of Hand Stencils in El Castillo Cave (Spain) Through Geomatic Techniques

Archaeometry, EarlyView.
ABSTRACT We present the application of a new quantitative approach to space study in Palaeolithic cave art. Using GIS, we analysed the distribution and position of hand stencils in El Castillo cave to track the gestures and behaviours of Palaeolithic societies.
Olga Spaey, Iñaki Intxaurbe, Iñigo Urrestarazu‐Porta, Martin Arriolabengoa, Sergio Salazar, Verónica Fernández‐Navarro, Aritz Irurtzun, Diego Garate   +7 more
wiley   +1 more source

Correction: Omentum-Derived Mesenchymal Stem Cells Promote Antibacterial Effects and Protect Endothelial Functions via PAI-1. [PDF]

Stem Cell Rev Rep
Castro Ramos A, Vuong CK, Fukushige M, Ushijima Y, Morikawa K, Osaka M, Tokunaga C, Hiramatsu Y, Ohneda O.   +8 more
europepmc   +1 more source

Anchors or relational risks? Educator and psychologist narratives of attachment in child–robot relationships

British Journal of Educational Psychology, EarlyView.
Abstract Background As AI‐enabled social robots become more common in schools, children may form strong emotional bonds with them despite robots not being caregivers and lacking the capacities for “true” attachment. Given limited understanding of potential risks and safeguards, professional perspectives are needed to inform responsible design and ...
Dimitris Pnevmatikos, Panagiota Christodoulou   +1 more
wiley   +1 more source

The expanding landscape of adipokines: emerging roles of PAI-1 and vaspin in cardiometabolic diseases. [PDF]

Front Endocrinol (Lausanne)
Kocabas S, Sanlier N.
europepmc   +1 more source

Worldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study

Clinical &Experimental Allergy, EarlyView.
Global Asthma Network Phase I surveyed children, adolescents, and adults worldwide to assess the prevalence of asthma, rhinoconjunctivitis, and eczema. Human Development Index (HDI) and Gini inequality index (GinI) were important explanatory factors for prevalence variability of these conditions, with hotspots in areas with high HDI and high GinI ...
Luis García‐Marcos, Chen‐Yuan Chiang, M. Innes Asher, Guy B. Marks, Asma El Sony, Refiloe Masekela, Karen Bissell, Eamon Ellwood, Philippa Ellwood, Neil Pearce, David P. Strachan, A. Elena Martínez‐Torres, Manuel Sánchez‐Solís, Kevin Mortimer, Eva Morales, The Global Asthma Network Phase I Study Group   +15 more
wiley   +1 more source

Targeted Interference with USF2 Binding to the SERPINE1 Proximal Promoter E-Box in Dual Mutant p53^R282Q,H179Y Human Keratinocytes Inhibits Serum-/TGF-β1-Induced SERPINE1 Expression and Stimulates Epithelial Cell Proliferation. [PDF]

Biomedicines
Higgins SP, Czekay RP, Higgins CE, Higgins PJ.   +3 more
europepmc   +1 more source

Empowering Parents in Child Protection: An Evaluation of the Parental Advocacy and Information Service (PAIS) in Ireland

Child &Family Social Work, EarlyView.
ABSTRACT Parental advocacy represents a crucial response to the marginalization of parents within child protection systems, aiming to empower them by amplifying their voices, ensuring their participation and supporting them through complex legal and bureaucratic processes.
Shane Powell, Emilia Preter, Clive Diaz, Vicky Hansly   +3 more
wiley   +1 more source