Results 131 to 140 of about 203,517 (263)
Advanced Science, EarlyView.Postoperative cardiac adhesions lead to numerous difficulties in reoperation procedures. Here, a thermo‐responsive in situ formed hydrogel is shown to can reliably cover the wounds after a convenient spraying or injection and significantly reduce adhesion formation in primary and recurrent cardiac injury adhesion models.
Kun Shi +11 more
wiley +1 more source
Early Stratification of Patients at Risk for Postoperative Complications after Elective Colectomy [PDF]
arXiv, 2018 Stratifying patients at risk for postoperative complications may facilitate timely and accurate workups and reduce the burden of adverse events on patients and the health system. Currently, a widely-used surgical risk calculator created by the American College of Surgeons, NSQIP, uses 21 preoperative covariates to assess risk of postoperative ...
arxiv
How Much Does It Hurt: A Deep Learning Framework for Chronic Pain Score Assessment [PDF]
arXiv, 2020 Chronic pain is defined as pain that lasts or recurs for more than 3 to 6 months, often long after the injury or illness that initially caused the pain has healed. The "gold standard" for chronic pain assessment remains self report and clinical assessment via a biopsychosocial interview, since there has been no device that can measure it.
arxiv
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
Advanced Science, EarlyView.This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang +9 more
wiley +1 more source
Mathematical models for pain: a systematic review [PDF]
arXiv, 2020 There is no single prevailing theory of pain that explains its origin, qualities, and alleviation. Although many studies have investigated various molecular targets for pain management, few have attempted to examine the etiology or working mechanisms of pain through mathematical or computational techniques.
arxiv
Advanced Science, EarlyView.Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang +9 more
wiley +1 more source
BJA Open, 2023 Background: Laparoscopic hysterectomy is often carried out as day-stay surgery. Minimising postoperative pain is therefore of utmost importance to ensure timely discharge from hospital.
Kristian D. Friesgaard +4 more
doaj
Electrochemical‐Genetic Programming of Protein‐Based Magnetic Soft Robots for Active Drug Delivery
Advanced Science, EarlyView.This manuscript presents a protein‐based soft robot for active drug delivery. Stimuli‐responsive protein is rationally designed and processed into the substrate of robots. Superparamagnetic Fe3O4 nanoparticles are patterned on the substrate using an electrochemical method, enabling the robot to respond to external physical fields.
Hang Zhao +12 more
wiley +1 more source
Journal of Pain Research, 2023 Ryan Sica,1 Jenna M Wilson,1 Erin J Kim,1 Deborah J Culley,1,2 Samantha M Meints,1 Kristin L Schreiber1 1Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; 2Department of
Sica R +5 more
doaj