Results 261 to 270 of about 6,621,054 (405)

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

open access: yesAdvanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer   +8 more
wiley   +1 more source

Association of different pain patterns with physical function in participants with knee osteoarthritis: data from the osteoarthritis initiative. [PDF]

open access: yesJ Orthop Surg Res
Li S   +11 more
europepmc   +1 more source

Machine Learning‐Based Design of 3D‐Printable Microneedles for Enhanced Tissue Anchoring with Reduced Tissue Damage

open access: yesAdvanced Engineering Materials, EarlyView.
A machine learning‐driven framework is introduced to optimize 3D‐printable microneedles for enhanced tissue anchoring and reduced insertion damage. The optimized design achieves a 6.0‐fold improvement in pull‐out‐to‐penetration energy ratio over conventional shapes.
Jegyeong Ryu   +5 more
wiley   +1 more source

Living with pain-a systematic review on patients' subjective experiences. [PDF]

open access: yesSyst Rev
Christidis M   +6 more
europepmc   +1 more source

RHIZOTOMY FOR THE RELIEF OF PAIN [PDF]

open access: green, 1918
CHARLES H. FRAZIER
openalex   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht   +5 more
wiley   +1 more source

Human brain mechanisms of pain perception and regulation in health and disease

open access: yesEuropean Journal of Pain, 2005
A. Apkarian   +3 more
semanticscholar   +1 more source

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