Results 31 to 40 of about 4,352,567 (313)

Resistivity in warm dense plasmas beyond the average-atom model

open access: yes, 2009
The exploration of atomic properties of strongly coupled partially degenerate plasmas, also referred to as warm dense matter, is important in astrophysics, since this thermodynamic regime is encountered for instance in Jovian planets' interior.
Benage   +18 more
core   +1 more source

Cerebral organoids and their potential for studies of brain diseases in domestic animals

open access: yesVeterinary Research, 2021
The brain is a complex organ and any model for studying it in its normal and pathological aspects becomes a tool of choice for neuroscientists. The mastering and dissemination of protocols allowing brain organoids development have paved the way for a ...
Bertrand Pain   +2 more
doaj   +1 more source

Organoïdes hypophysaires : des outils pour caractériser le développement, la plasticité et les pathologies hypophysaires ?

open access: yesINRAE Productions Animales, 2023
L’hypophyse, glande maitresse de l’organisme, occupe une place centrale dans le système endocrinien. Composée d’un lobe antérieur (adénohypophyse) responsable de la synthèse d’hormones et d’un lobe postérieur (neurohypophyse) de structure nerveuse, elle
Catherine TARAGNAT   +2 more
doaj   +1 more source

The effect of some environmental factors on rapid mass movement in the Hunua Ranges, New Zealand [PDF]

open access: yes, 1969
This paper describes some of the relationships between rapid mass movement and environmental factors in the Hunua Ranges. Extreme climatic events appear to be important in triggering mass movement, while vegetation has a marked effect on mass movement ...
Pain, C.F.
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Exploring the significance of domestic investment for foreign direct investment in China: a city-network approach [PDF]

open access: yes, 2019
This paper uses a network approach and a negative binomial regression model (NBRM) to shed light on the association between Domestic Investment (DI) and Foreign Direct Investment (FDI) in interlinking Chinese cities in a space of flows.
Pain, Kathy, Shia, Shuai, Wall, Ronald
core   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

Comparison of the Efficacy and Safety of Temporary Spinal Cord Stimulation versus Pulsed Radiofrequency for Postherpetic Neuralgia: A Prospective Randomized Controlled Trial

open access: yesPain Research and Management, 2022
Objectives. The objective of this study is to compare the safety and effectiveness of the temporary spinal cord stimulation (SCS) versus pulsed radiofrequency (PRF) in treating postherpetic neuralgia (PHN). Methods.
Xiaohong Li   +6 more
doaj   +1 more source

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