Results 31 to 40 of about 4,741,499 (307)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

A Literature Review to Evaluate the Choice and Use of Visual Methods

open access: yesInternational Journal of Qualitative Methods, 2012
Visual methods are accepted tools for qualitative research and are increasingly used in a wide range of disciplines, such as sociology, psychology, geography, and health care.
Helen Pain MSc
doaj   +1 more source

Metaheuristic Approach of Multi-Objective Optimization during EDM Process [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences, 2018
In modern-day manufacturing Electric Discharge Machining (EDM) process has successfully placed itself in the domain of precision machining and generating complex geometries where secondary machining processes are eliminated. In this research paper, a die
Goutam Kumar Bose, Pritam Pain
doaj   +1 more source

Accounting for highly excited states in detailed opacity calculations

open access: yes, 2015
In multiply-charged ion plasmas, a significant number of electrons may occupy high-energy orbitals. These "Rydberg" electrons, when they act as spectators, are responsible for a number of satellites of X-ray absorption or emission lines, yielding a ...
Gilleron, Franck, Pain, Jean-Christophe
core   +1 more source

Doubling your payoff: winning pain relief engages endogenous pain inhibition [PDF]

open access: yes, 2015
When in pain, pain relief is much sought after, particularly for individuals with chronic pain. In analogy to augmentation of the hedonic experience (“liking”) of a reward by the motivation to obtain a reward (“wanting”), the seeking of pain relief in ...
Ahmed, Alysha-Karima   +4 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Educación, Psicopedagogía y ética social

open access: yesDiálogos Pedagógicos, 2012
En el marco del Programa de Posgrado en Clínica del Aprender dictado en nuestra Facultad de Educación bajo la dirección de la Lic. Dora Laino, la reconocida psicopedagoga Dra. Sara Paín dictó la conferencia: “La psicopedagogía, ¿supone una ética social?”.
Sara Paín
doaj  

Suffering Pains [PDF]

open access: yes, 2019
The paper aims at clarifying the distinctions and relations between pain and suffering. Three negative theses are defended: 1. Pain and suffering are not identical. 2.
Massin, Olivier
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Strong, Weak and Merging Lines in Atomic Spectra

open access: yesPlasma
We present analytical estimates for the maximum line strength in a transition array, as well as for the numbers of strong and weak lines. For that purpose, two main assumptions are used as concerns the line strength distribution.
Jean-Christophe Pain
doaj   +1 more source

Home - About - Disclaimer - Privacy