Results 101 to 110 of about 8,115 (216)

NGF – the TrkA to successful pain treatment [PDF]

open access: yes, 2012
Chronic pain arising from various pathological conditions such as osteoarthritis, low back or spinal injuries, cancer, and urological chronic pelvic pain syndromes presents significant challenges in diagnosis and treatment.
Kumar, Vinayak, Mahal, Brandon
core   +1 more source

Thermal quantitative sensory testing in healthy Dutch children and adolescents standardized test paradigm and Dutch reference values [PDF]

open access: yes, 2017
Background: Quantitative sensory testing (QST) is often used to measure children's and adults' detection- and pain thresholds in a quantitative manner.
Bosch, G.E. (Gerbrich) van den   +3 more
core   +3 more sources

Congenital insensitivity to pain with anyhydrosis: morphological studies of skin and peripheral nerves

open access: yesThe Turkish Journal of Pediatrics, 1989
Two male siblings born to consanguineous parents, with the diagnosis of congenital insensitivity to pain with anhydrosis are evaluated. The patients presented with unexplained bouts of fever, self-mutilation, repeated trauma and inability to sweat.
R Eker   +4 more
doaj  

Preserved emotional awareness of pain in a patient with extensive bilateral damage to the insula, anterior cingulate, and amygdala [PDF]

open access: yes, 2016
Functional neuroimaging investigations of pain have discovered a reliable pattern of activation within limbic regions of a putative "pain matrix" that has been theorized to reflect the affective dimension of pain.
A Biemond   +72 more
core   +1 more source

A disease mutation reveals a role for Nav1.9 in acute itch [PDF]

open access: yes, 2018
Itch (pruritis) and pain represent two distinct sensory modalities; yet both have evolved to alert us to potentially harmful external stimuli. Compared with pain, our understanding of itch is still nascent.
Bosmans, Frank   +5 more
core   +1 more source

Update Review and Clinical Presentation in Congenital Insensitivity to Pain and Anhidrosis

open access: yesCase Reports in Pediatrics, 2015
Introduction. Congenital insensitivity to pain and anhidrosis (CIPA) or hereditary sensory and autonomic neuropathy type IV is an extremely rare syndrome.
L. M. Pérez-López   +4 more
doaj   +1 more source

Main therapeutic and rehabilitation actions in patients with congenital insensitivity to pain

open access: yesUniversidad Médica Pinareña, 2020
Introduction: congenital insensitivity to pain is a hereditary whose main characteristic is absolute analgesia to pain. Objective: to describe the main existing therapeutic actions for patients with congenital insensitivity to pain in its diverse ...
Noel Jesús Niebla-Gómez   +2 more
doaj  

Congenital Insensitivity to Pain: A Case Report and Review of the Literature

open access: yesCase Reports in Neurological Medicine, 2014
Congenital insensitivity to pain (CIP) is a rare autosomal recessive genetic disease caused by mutations in the SCN9A gene. We report a patient with the clinical features consistent with CIP in whom we detected a novel homozygous G2755T mutation in exon ...
Leema Reddy Peddareddygari   +2 more
doaj   +1 more source

Congenital Insensitivity to Pain [PDF]

open access: yesJournal of the Royal Society of Medicine, 1991
openaire   +2 more sources

Catecholamines and congenital pain insensitivity.

open access: yesBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1985
The congenital pain insensitivity syndrome is accompanied by: a) the presence of a yellow-brown pigment in the basal layer of the epidermis with the histochemical properties of melanin, b) decrease of urinary and blood concentration of dopamine and norepinephrine, c) excretion of melanin and of an abnormal as yet unidentified phenolic metabolite, d ...
I, Raw, B J, Schmidt, J, Merzel
openaire   +1 more source

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