Results 101 to 110 of about 10,885,442 (404)

Transplantation of miR-216a-5p-overexpressing mesenchymal stem cells encapsulated in a thermosensitive hydrogel promotes functional recovery in a rat model of spinal cord injury

European Journal of Medical Research
To evaluate the therapeutic efficacy of mesenchymal stem cells (MSCs) overexpressing miR-216a-5p delivered via a thermosensitive hydrogel in a rat model of spinal cord injury (SCI).
Zhi Dou, Liangliang He, Jianning Yue, Wenxing Zhao, Hongyan Wang, Jie Lu, Chao Wang, Liqiang Yang   +7 more
doaj   +1 more source

Systematically searching for and assessing the literature for self-management of chronic pain: A lay users' perspective [PDF]

, 2014
© 2014 Schofield et al.; licensee BioMed Central Ltd. Background: The Engaging with older adults in the development of strategies for the self management of chronic pain (EOPIC) study aims to design and develop self management strategies to enable older ...
Anthony, G, Clarke, A, Fowler, S, Jones, D, Marsh, R, Martin, D, McNamee, P, Morrison, M, Morrison, R, Schofield, Patricia, Smith, BH, Stewart, C   +11 more
core   +9 more sources

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU

Critical Care Medicine, 2018
Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design: Thirty-two international experts, four methodologists, and four critical illness survivors met
J. Devlin, Y. Skrobik, C. Gélinas, D. Needham, A. Slooter, P. Pandharipande, P. Watson, G. Weinhouse, M. Nunnally, B. Rochwerg, Michele C Balas, M. van den Boogaard, K. Bosma, N. Brummel, G. Chanques, L. Denehy, X. Drouot, G. Fraser, Jocelyn Harris, A. Joffe, M. Kho, J. Kress, Julie A. Lanphere, S. McKinley, K. Neufeld, M. Pisani, J. Payen, B. Pun, K. Puntillo, R. Riker, B. Robinson, Y. Shehabi, P. Szumita, C. Winkelman, J. Centofanti, Carrie Price, Sina Nikayin, C. Misak, P. Flood, Ken Kiedrowski, W. Alhazzani   +40 more
semanticscholar   +1 more source

Patients’ and emergency clinicians’ perceptions of improving pre-hospital pain management: a qualitative study [PDF]

, 2013
Background: The authors aimed to investigate patients' and practitioners' views and experiences of pre-hospital pain management to inform improvements in care and a patient-centred approach to treatment. Methods: This was a qualitative study involving a
Iqbal, Mohammad, Siriwardena, A. Niroshan, Spaight, Anne   +2 more
core   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

Effectiveness and cost-effectiveness of a novel, group self-management course for adults with chronic musculoskeletal pain: study protocol for a multicentre, randomised controlled trial (COPERS) [PDF]

, 2013
Introduction: Chronic musculoskeletal pain is a common condition that often responds poorly to treatment. Self-management courses have been advocated as a non-drug pain management technique, although evidence for their effectiveness is equivocal. We
Bremner, Stephen, Carnes, Dawn, Eldridge, Sandra, Homer, Kate, Pincus, Tamar, Rahman, A (Anisur), Taylor, Stephanie J. C., Underwood, Martin   +7 more
core   +4 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

European Pain Federation (EFIC) position paper on appropriate use of cannabis‐based medicines and medical cannabis for chronic pain management

European Journal of Pain, 2018
Cannabis‐based medicines are being approved for pain management in an increasing number of European countries. There are uncertainties and controversies on the role and appropriate use of cannabis‐based medicines for the management of chronic pain.
W. Häuser, David P Finn, E. Kalso, N. Krčevski-Škvarč, H. Kress, B. Morlion, S. Perrot, M. Schäfer, C. Wells, S. Brill   +9 more
semanticscholar   +1 more source

Using geographical information systems for management of back-pain data [PDF]

, 2002
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2002 MCB UP LtdIn the medical world, statistical visualisation has largely been confined to the realm of relatively simple ...
De Souza, LH, Frank, AO, Ghinea, G, Gill, D   +3 more
core   +1 more source